Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Isoproterenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 7/20 | 1.00 |
| ▸ | ADRB1 known ✓ | P08588 | 5/20 | 1.00 |
| ▸ | ADRB3 known ✓ | P13945 | 5/20 | 0.97 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 1.00 |
| ▸ | TSHR | P16473 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.97 |
| ▸ | MTOR | P42345 | 3/20 | 0.97 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.97 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.97 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoproterenol SCHEMBL9614622 | 1.00 | MAPT (1.00) | MAPTADRB2KDM4ETDP1ADRB1 | |
| Isoproterenol SCHEMBL28872988 | 1.00 | MAPT (1.00) | MAPTADRB2KDM4ETDP1ADRB1 | |
| Isoproterenol SCHEMBL3672791 | 1.00 | MAPT (1.00) | MAPTADRB2KDM4ETDP1ADRB1 | |
| Levisoprenaline SCHEMBL4745572 | 1.00 | MAPT (1.00) | MAPTADRB2KDM4ETDP1ADRB1 | |
| Isoproterenol SCHEMBL4166 | 0.98 | MAPT (1.00) | MAPTADRB2KDM4ETDP1ADRB1 | |
| Isoproterenol SCHEMBL3253794 | 0.98 | MAPT (1.00) | MAPTADRB2KDM4ETDP1ADRB1 | |
| Isoproterenol SCHEMBL29386243 | 0.98 | MAPT (1.00) | MAPTADRB2KDM4ETDP1ADRB1 | |
| Isoproterenol SCHEMBL4165 | 0.98 | MAPT (1.00) | MAPTADRB2KDM4ETDP1ADRB1 | |
| Levisoprenaline SCHEMBL250806 | 0.98 | MAPT (1.00) | MAPTADRB2KDM4ETDP1ADRB1 | |
| Isoproterenol SCHEMBL29519146 | 0.98 | MAPT (1.00) | MAPTADRB2KDM4ETDP1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3741 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250387343-A1 | Nanoparticle Compositions and Methods for Synthesis Thereof | ICEUTICA PTY LTD (AU) | 2025-12-25 | — | — | US | claimed |
| CN-119896184-A | Zebra fish model with qi deficiency and blood stasis syndrome, preparation method and application thereof | 杭州环特生物科技股份有限公司 | 2025-04-29 | — | — | CN | claimed |
| CN-119768510-A | Methods and compositions for producing hematopoietic endothelial cells from pluripotent stem cells | 特雷尔赫德生物系统股份有限公司 | 2025-04-04 | — | — | CN | claimed |
| US-20250066727-A1 | COMPOSITIONS AND METHODS FOR CULTURING STEM CELLS | BEIJING THERAXYTE BIOSCIENCE CO., LTD. (CN) | 2025-02-27 | — | — | US | claimed |
| CN-119504453-A | New preparation method of isoprenaline hydrochloride | 华仁医学研究(安徽)有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-118255674-B | Method for preparing isoprenaline hydrochloride | 北京均大检测科技有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-119054650-A | Animal model construction method and application of qi deficiency and blood stasis type slow transmission functional constipation | 中国科学院长春应用化学研究所 | 2024-12-03 | — | — | CN | claimed |
| EP-4457337-A1 | COMPOSITIONS AND METHODS FOR CULTURING STEM CELLS | Beijing Theraxythe Bioscience Co. Ltd. (CN) | 2024-11-06 | — | — | EP | claimed |
| CN-118421568-B | Culture medium of induced pluripotent stem cells and application thereof | 深圳市中佳生物医疗科技有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-118541473-A | Compositions and methods for culturing stem cells | 北京思珞赛生物科技有限公司 | 2024-08-23 | — | — | CN | claimed |
| US-5192548-A | DEVICE | RIKER LABORATOIRES, INC. (US) | 1993-03-09 | — | — | US | claimed |
| EP-0487520-A4 | COMPRESSED POWDER MEDICAMENTS | — | 1992-08-12 | — | — | EP | claimed |
| US-5132114-A | Compositions and methods of manufacture of compressed powder medicaments | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1992-07-21 | — | — | US | claimed |
| EP-0487520-A1 | COMPRESSED POWDER MEDICAMENTS. | ANESTA CORP (US) | 1992-06-03 | — | — | EP | claimed |
| WO-1992000062-A1 | THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-01-09 | — | — | WO | claimed |
| EP-0455463-A1 | Packaging for microdoses of powdered medicament for inhalation | RIKER LABORATORIES, INC. (US) | 1991-11-06 | — | — | EP | claimed |
| WO-1991003099-A1 | COMPRESSED POWDER MEDICAMENTS | ANESTA CORPORATION (US) | 1991-03-07 | — | — | WO | claimed |
| EP-0189861-A2 | Percutaneous absorption accelerator for ionic water-soluble medicine | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | claimed |
| US-4352789-A | COATING OF PERFLUORINATED SURFACTANT; INHALANTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-10-05 | — | — | US | claimed |
| US-4038417-A | ADRENERGIC STIMULATING AGENTS, ISOPROTERENOL | NELSON RESEARCH & DEVELOPMENT COMPANY (US) | 1977-07-26 | — | — | US | claimed |