Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.74 |
| ▸ | NPC1 | O15118 | 10/20 | 0.74 |
| ▸ | RAB9A | P51151 | 10/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.74 |
| ▸ | HPGD | P15428 | 9/20 | 0.74 |
| ▸ | TP53 | P04637 | 5/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.74 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 11/20 | 0.62 |
| ▸ | PKM | P14618 | 5/20 | 0.62 |
| ▸ | GFER | P55789 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | POLB | P06746 | 6/20 | 0.62 |
| ▸ | GAA | P10253 | 5/20 | 0.62 |
| ▸ | USP2 | O75604 | 4/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17867450 | 0.94 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL29596534 | 0.92 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL29906364 | 0.92 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL9767334 | 0.92 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL57009 | 0.88 | POLB (0.57) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL12351269 | 0.87 | MEN1 (0.76) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL15443912 | 0.87 | PRMT1 (0.82) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL15443952 | 0.86 | PRMT1 (0.75) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL31063849 | 0.85 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL758845 | 0.85 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975416-B2 | Antibacterial compounds | SUMMIT CORPORATION PLC (GB) | 2015-03-10 | — | — | US | claimed |
| EP-2373631-B1 | ANTIBACTERIAL COMPOUNDS | SUMMIT CORP PLC (GB) | 2015-02-25 | — | — | EP | claimed |
| US-4390596-A | POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER | RHONE-POULENC INDUSTRIES (FR) | 1983-06-28 | — | — | US | claimed |
| US-4238591-A | BIS-MALEIMIDE, SILANEDIOL OR SILOXANE | RHONE-POULENC INDUSTRIES (FR) | 1980-12-09 | — | — | US | claimed |
| US-4225498-A | Preparation of N-substituted oligo-imides | RHONE-POULENC INDUSTRIES (FR) | 1980-09-30 | — | — | US | claimed |
| US-9763925-B2 | Antibacterial compounds | SUMMIT THERAPEUTICS PLC (GB) | 2017-09-19 | — | — | US | disclosed |
| EP-3095783-A1 | ANTIBACTERIAL COMPOUNDS | Summit Corporation Plc (GB) | 2016-11-23 | — | — | EP | disclosed |
| US-20160184283-A1 | ANTIBACTERIAL COMPOUNDS | SUMMIT (OXFORD) LIMITED (GB) | 2016-06-30 | — | — | US | disclosed |
| US-9314456-B2 | Antibacterial compounds | SUMMIT THERAPEUTICS PLC (GB) | 2016-04-19 | — | — | US | disclosed |
| EP-2907813-A1 | Antibacterial Compound | Summit Corporation Plc (GB) | 2015-08-19 | — | — | EP | disclosed |
| US-20150150861-A1 | ANTIBACTERIAL COMPOUNDS | SUMMIT (OXFORD) LIMITED (GB) | 2015-06-04 | — | — | US | disclosed |
| US-8975416-B2 | Antibacterial compounds | SUMMIT CORPORATION PLC (GB) | 2015-03-10 | — | — | US | disclosed |
| US-4013600-A | STORAGE STABILITY | RHONE-POULENC INDUSTRIES (FR) | 1977-03-22 | — | — | US | disclosed |
| US-4012361-A | Heat-stable polyimide resins from a bis-imide, a polyamine and an alazine | RHONE-POULENC S.A. (FR) | 1977-03-15 | — | — | US | disclosed |
| US-4010220-A | AMINO COMPOUND, POLYURETHANE ELASTOMER | RHONE-POULENC INDUSTRIES (FR) | 1977-03-01 | — | — | US | disclosed |
| US-4005154-A | Curing 1,2-epoxy with prepolymer based on polyamines and oligomers possessing imide groups | RHONE-POULENC S.A. (FR) | 1977-01-25 | — | — | US | disclosed |
| US-3998904-A | POLYAMINES WITH IMIDE GROUPS | RHONE-POULENC S.A. (FR) | 1976-12-21 | — | — | US | disclosed |
| US-3970714-A | Heat-stable polyimide resin modified by unsaturated polyester | RHONE-POULENC S.A. (FR) | 1976-07-20 | — | — | US | disclosed |
| US-3966678-A | Maleic anhydride-polyaldimine prepolymers | RHONE-POULENC S.A. (FR) | 1976-06-29 | — | — | US | disclosed |
| US-3933745-A | Imide copolymers possessing hydroxyl groups | RHONE-POULENC S.A. (FR) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160184283-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, RPN2, ALPI | ALDH1A1 1088/4885SMN1; SMN2 2597/4885NPC1 512/4885 |
| US-20150150861-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, RPN2, ALPI | ALDH1A1 1088/4885SMN1; SMN2 2597/4885NPC1 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.