Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3473227 | 0.82 | MEN1 (0.66) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL13875704 | 0.81 | ADORA1 (0.58) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL21765569 | 0.81 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL782567 | 0.80 | MEN1 (1.00) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL10329709 | 0.80 | HRH4 (0.70) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4645889 | 0.79 | MAPT (0.62) | MEN1KMT2AALDH1A1MAPTAGTR1 | |
| SCHEMBL3220814 | 0.78 | MEN1 (0.59) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL3451792 | 0.78 | MEN1 (0.59) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4647181 | 0.77 | MAPT (0.60) | MEN1KMT2AALDH1A1MAPTAGTR1 | |
| SCHEMBL24287409 | 0.77 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | disclosed |
| US-9321735-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2016-04-26 | — | — | US | disclosed |
| US-8785630-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2014-07-22 | — | — | US | disclosed |
| US-20130267705-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2013-10-10 | — | — | US | disclosed |
| US-20130150365-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2013-06-13 | — | — | US | disclosed |
| EP-2595965-A1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | Vestaron Corporation (US) | 2013-05-29 | — | — | EP | disclosed |
| US-8389718-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2013-03-05 | — | — | US | disclosed |
| US-20120022066-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2012012528-A1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | Vestaron Corporation (US) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150365-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | MEN1 4237/4885KMT2A 1053/4885SMN1; SMN2 3920/4885 |
| US-20120022066-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | MEN1 4237/4885KMT2A 1053/4885SMN1; SMN2 3920/4885 |
| US-20130267705-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | MEN1 4237/4885KMT2A 1053/4885SMN1; SMN2 3920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.