SCHEMBL416637

SCHEMBL416637

CSCCC(N)C(=O)NC(CS)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(CCCCN)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NTSR2 O95665 11/20 0.47
NTSR1 P30989 11/20 0.47
APLNR P35414 2/20 0.46
SORT1 Q99523 3/20 0.45
CAPN1 P07384 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL416638 1.00 NTSR2 (0.47) NTSR2NTSR1APLNRSORT1CAPN1
SCHEMBL414730 0.98 NTSR2 (0.48) NTSR2NTSR1APLNRSORT1
SCHEMBL414731 0.98 NTSR2 (0.48) NTSR2NTSR1APLNRSORT1
SCHEMBL417517 0.94 OPRM1 (0.45) NTSR2NTSR1APLNRSORT1
SCHEMBL417518 0.94 OPRM1 (0.45) NTSR2NTSR1APLNRSORT1
SCHEMBL416536 0.93 OPRK1 (0.46) NTSR2NTSR1APLNR
SCHEMBL416535 0.93 OPRK1 (0.46) NTSR2NTSR1APLNR
SCHEMBL416858 0.91 NTSR2 (0.49) NTSR2NTSR1SORT1CAPN1
SCHEMBL416859 0.91 NTSR2 (0.49) NTSR2NTSR1SORT1CAPN1
SCHEMBL416569 0.91 OPRK1 (0.45) NTSR2NTSR1APLNRSORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120020878-A1 FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2012-01-26 US disclosed