Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.57 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172404 | 0.88 | NR3C1 (0.46) | NR3C1SCN9ASCN10AKHKSCN5A | |
| SCHEMBL4171102 | 0.80 | NR3C1 (0.65) | NR3C1CYP17A1CYP1A2SCN9ASCN10A | |
| Hydrochloric Acid SCHEMBL30403640 | 0.76 | NR3C1 (0.43) | NR3C1KHK | |
| SCHEMBL4158339 | 0.73 | NR3C1 (0.76) | NR3C1SCN9ASCN10ACCR1 | |
| SCHEMBL4168041 | 0.73 | NR3C1 (1.00) | NR3C1 | |
| SCHEMBL4168046 | 0.73 | NR3C1 (0.72) | NR3C1CYP17A1CYP1A2SCN9ASCN10A | |
| SCHEMBL4158857 | 0.73 | NR3C1 (0.80) | NR3C1CYP17A1CYP1A2CCR1 | |
| SCHEMBL303982 | 0.72 | CYP17A1 (0.56) | NR3C1CYP17A1CYP1A2CCR1 | |
| SCHEMBL1238827 | 0.72 | NOTUM (0.56) | MAPTTP53KHKHRH4 | |
| SCHEMBL1413366 | 0.72 | NOTUM (0.56) | MAPTTP53KHKHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170898-A1 | Sulphonamide Derivatives as Modulators of the Glucocorticoid Receptor | BENGTSSON MALENA | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170898-A1 | Sulphonamide Derivatives as Modulators of the Glucocorticoid Receptor | NR3C1, NR3C2, NR5A1 | NR3C1 1/4885CYP17A1 109/4885CYP1A2 887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.