Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266851 | 0.88 | PRKAB2 (0.33) | — | |
| SCHEMBL3266861 | 0.88 | PRKAB2 (0.33) | — | |
| SCHEMBL3266855 | 0.88 | PRKAB2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL4162703 | 0.87 | HTR6 (0.36) | HTR6 | |
| Hydrochloric Acid SCHEMBL4162707 | 0.87 | HTR6 (0.36) | HTR6 | |
| SCHEMBL4157558 | 0.85 | HTR6 (0.31) | HTR6 | |
| Butyric Acid SCHEMBL4166813 | 0.85 | BRD4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL4158188 | 0.82 | HTR6 (0.32) | HTR6 | |
| Hydrochloric Acid SCHEMBL4158190 | 0.82 | HTR6 (0.32) | HTR6 | |
| SCHEMBL4166215 | 0.81 | HTR6 (0.34) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426437-B2 | Pyrroloquinoline derivatives and their use as protein kinases inhibitors | PIERRE FABRE MEDICAMENT (FR) | 2013-04-23 | — | — | US | disclosed |
| US-20090042876-A1 | Pyrroloquinoline Derivatives And Their Use As Protein Kinases Inhibitors | PIERRE FABRE MEDICAMENT (FR) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042876-A1 | Pyrroloquinoline Derivatives And Their Use As Protein Kinases Inhibitors | MAP3K1, MAP3K2, MAP3K7 | HTR6 4018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.