SCHEMBL416725

SCHEMBL416725

FC(F)(F)C(F)(F)C(F)(F)OC(F)(F)C(F)(F)CCS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9352762 0.79
SCHEMBL13847894 0.77
SCHEMBL1094381 0.77
SCHEMBL420082 0.77 ALDH1A1 (0.33)
SCHEMBL13847893 0.74
SCHEMBL14802501 0.72
SCHEMBL624254 0.72 LMNA (0.30)
SCHEMBL17292693 0.71 LMNA (0.30)
SCHEMBL3783688 0.70 LMNA (0.35)
SCHEMBL3772578 0.70 LMNA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2215098-B1 FLUOROALKYL SILANES DU PONT (US) 2014-08-20 EP disclosed
EP-2662354-A2 Sulfur containing fluoroalkyl amines and isocyanates E. I. du Pont de Nemours and Company (US) 2013-11-13 EP disclosed
EP-2215056-B1 SULFUR CONTAINING FLUOROALKYL AMINES AND ISOCYANATES DU PONT (US) 2013-10-30 EP disclosed
US-8501952-B2 Fluoroalkyl silanes E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-08-06 US disclosed
US-8420826-B2 Fluoroalkyl silanes E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-04-16 US disclosed
US-8153846-B2 Sulfur containing fluoroalkyl amines and isocyanates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-04-10 US disclosed
US-20120022267-A1 FLUOROALKYL SILANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-26 US disclosed
US-20120022266-A1 FLUOROALKYL SILANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-26 US disclosed
US-8058463-B2 Fluorosilanes E. I. DU PONT DE NEMOURS AND COMPNAY (US) 2011-11-15 US disclosed
EP-2215056-A2 SULFUR CONTAINING FLUOROALKYL AMINES AND ISOCYANATES E. I. du Pont de Nemours and Company (US) 2010-08-11 EP disclosed
EP-2215098-A1 FLUOROALKYL SILANES E. I. du Pont de Nemours and Company (US) 2010-08-11 EP disclosed
WO-2009073595-A1 FLUOROALKYL SILANES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-11 WO disclosed
WO-2009073592-A2 SULFUR CONTAINING FLUOROALKYL AMINES AND ISOCYANATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-11 WO disclosed
US-20090143608-A1 SULFUR CONTAINING FLUOROALKYL AMINES AND ISOCYANATES E. I. DU PONT DE NEMOURS AND COMPNAY 2009-06-04 US disclosed
US-20090143598-A1 FLUOROSILANES E.I. DU PONT DE NEMOURS AND COMPANY 2009-06-04 US disclosed