Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892252 | 0.92 | F10 (0.38) | FFAR1AKR1B1PPARGAGTR1F10 | |
| SCHEMBL4447793 | 0.92 | PPARA (0.37) | PPARGPPARDPPARA | |
| SCHEMBL1892167 | 0.91 | AGTR1 (0.40) | PPARGAGTR1F10 | |
| SCHEMBL1890807 | 0.91 | AGTR1 (0.39) | PPARGAGTR1F10 | |
| SCHEMBL2842769 | 0.90 | F10 (0.39) | PPARGAGTR1F10 | |
| SCHEMBL1891599 | 0.89 | TDP2 (0.40) | PPARGAGTR1F10 | |
| SCHEMBL1890328 | 0.89 | AGTR1 (0.41) | PPARGAGTR1F10 | |
| SCHEMBL1885570 | 0.89 | AGTR1 (0.38) | PPARGAGTR1F10 | |
| SCHEMBL1886835 | 0.88 | AGTR1 (0.38) | PPARGAGTR1F10 | |
| SCHEMBL1892360 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |