SCHEMBL416765

SCHEMBL416765

CCCCC[Si](CCCCC)CCCCC

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
THRB P10828 1/20 0.50
LMNA P02545 3/20 0.43
SLC22A1 O15245 3/20 0.39
SLC22A2 O15244 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
DNM1 Q05193 5/20 0.37
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17090785 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL17090776 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL419899 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL17090842 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
Bromide SCHEMBL20500227 0.96 TSHR (0.47) TSHRTHRBLMNASLC22A1SLC22A2
SCHEMBL1556049 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL17090791 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
Iodide SCHEMBL20500237 0.96 TSHR (0.47) TSHRTHRBLMNASLC22A1SLC22A2
Hydrochloric Acid SCHEMBL20500147 0.96 TSHR (0.47) TSHRTHRBLMNASLC22A1SLC22A2
SCHEMBL1480045 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1044 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3052229-B1 IMMOBILIZED METATHESIS TUNGSTEN OXO ALKYLIDENE CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS VERBIO VER BIOENERGIE AG (DE) 2021-02-24 EP claimed
CN-112351987-A Non-coordinating anionic activators containing cations with large alkyl groups 埃克森美孚化学专利公司 2021-02-09 CN claimed
US-10427146-B2 Immobilized metathesis tungsten oxo alkylidene catalysts and use thereof in olefin metathesis XIMO AG (CH) 2019-10-01 US claimed
US-20160236185-A1 IMMOBILIZED METATHESIS TUNGSTEN OXO ALKYLIDENE CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS VERBIO SE (DE) 2016-08-18 US claimed
EP-3052229-A1 IMMOBILIZED METATHESIS TUNGSTEN OXO ALKYLIDENE CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS XiMo AG (CH) 2016-08-10 EP claimed
EP-1785413-B1 ARYLSULFONIC ACID COMPOUND AND USE THEREOF AS ELECTRON-ACCEPTOR MATERIAL NISSAN CHEMICAL IND LTD (JP) 2014-01-22 EP claimed
US-7736634-B2 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2010-06-15 US claimed
US-7595370-B2 Reacting cyclosiloxane with unsaturated organosilylated carboxylate monomer or copolymer under presence of catalyst; antifouling paints, marine systems PPG B.V. (NL) 2009-09-29 US claimed
US-7550760-B2 Polyacenes and electronic devices generated therefrom XEROX CORPORATION (US) 2009-06-23 US claimed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP claimed
US-20070235725-A1 Ethynylene acene polymers and electronic devices generated therefrom XEROX CORPORATION 2007-10-11 US claimed
EP-1476509-B1 SELF-POLISHING ANTIFOULING PAINT JOTUN AS (NO) 2007-04-11 EP claimed
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2006-06-29 US claimed
WO-2005118564-A2 METHODS FOR THE SYNTHESIS OF MILNACIPRAN AND CONGENERS THEREOF COLLEGIUM PHARMACEUTICAL, INC. (US) 2005-12-15 WO claimed
EP-1539861-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF Sigmakalon Services B.V. (NL) 2005-06-15 EP claimed
WO-2004007591-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF SIGMAKALON SERVICES B.V. (NL) 2004-01-22 WO claimed
EP-1380611-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SigmaKalon Group B.V. (NL) 2004-01-14 EP claimed
EP-1208167-B1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING SILICON-CONTAINING CO-POLYMERS AND FIBRES HEMPELS SKIBSFARVE FAB J C (DK) 2003-07-30 EP claimed
US-5663271-A Polysilanes and method for producing the same RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) 1997-09-02 US claimed
US-5508397-A Activated macrolactams ABBOTT LABORATORIES (US) 1996-04-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10427146-B2 Immobilized metathesis tungsten oxo alkylidene catalysts and use thereof in olefin metathesis CCR2, SIK2, CCRL2 TSHR 1560/4885THRB 3447/4885LMNA 3734/4885
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof C1R, C9, PCBP1 TSHR 3690/4885THRB 4122/4885LMNA 3271/4885
US-20160236185-A1 IMMOBILIZED METATHESIS TUNGSTEN OXO ALKYLIDENE CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS SIK2, CCR2, CCRL2 TSHR 1624/4885THRB 3449/4885LMNA 3605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.