Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 6/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329962 | 1.00 | TSHR (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL330199 | 1.00 | TSHR (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL330677 | 1.00 | TSHR (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL10947939 | 1.00 | TSHR (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL7815097 | 1.00 | TSHR (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL17225894 | 1.00 | TSHR (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL330198 | 1.00 | TSHR (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL10795468 | 1.00 | TSHR (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL10947943 | 1.00 | TSHR (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL7815100 | 1.00 | TSHR (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419394-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-OCTATRIENE-1-OIC ACID AND 2,4,6-OCTATRIENE-1-OL | GIULIANI S.p.A. (IT) | 2012-02-22 | — | — | EP | claimed |
| US-20120022282-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-OCTATRIENE-1-OIC ACID AND 2,4,6-OCTATRIENE-1-OL | GIULIANI S.P.A. (IT) | 2012-01-26 | — | — | US | claimed |
| WO-2010119117-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-OCTATRIENE-1-OIC ACID AND 2,4,6-OCTATRIENE-1-OL | GIULIANI S.P.A. (IT) | 2010-10-21 | — | — | WO | claimed |
| EP-2241543-A1 | Process for the preparation of 2,4,6-octatriene-1-oic acid and 2,4,6-octatriene-1-ol | Giuliani S.p.A. (IT) | 2010-10-20 | — | — | EP | claimed |
| EP-3041459-B1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI SPA (IT) | 2019-04-03 | — | — | EP | disclosed |
| US-20160213635-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI S.P.A. (IT) | 2016-07-28 | — | — | US | disclosed |
| EP-3041459-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | Giuliani S.p.A. (IT) | 2016-07-13 | — | — | EP | disclosed |
| WO-2015033276-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI S.P.A. (IT) | 2015-03-12 | — | — | WO | disclosed |
| EP-2419394-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-OCTATRIENE-1-OIC ACID AND 2,4,6-OCTATRIENE-1-OL | GIULIANI S.p.A. (IT) | 2012-02-22 | — | — | EP | disclosed |
| EP-2419394-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-OCTATRIENE-1-OIC ACID AND 2,4,6-OCTATRIENE-1-OL | GIULIANI S.p.A. (IT) | 2012-02-22 | — | — | EP | disclosed |
| US-20120022282-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-OCTATRIENE-1-OIC ACID AND 2,4,6-OCTATRIENE-1-OL | GIULIANI S.P.A. (IT) | 2012-01-26 | — | — | US | disclosed |
| US-20120022282-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-OCTATRIENE-1-OIC ACID AND 2,4,6-OCTATRIENE-1-OL | GIULIANI S.P.A. (IT) | 2012-01-26 | — | — | US | disclosed |
| WO-2010119117-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-OCTATRIENE-1-OIC ACID AND 2,4,6-OCTATRIENE-1-OL | GIULIANI S.P.A. (IT) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010119117-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-OCTATRIENE-1-OIC ACID AND 2,4,6-OCTATRIENE-1-OL | GIULIANI S.P.A. (IT) | 2010-10-21 | — | — | WO | disclosed |
| EP-2241543-A1 | Process for the preparation of 2,4,6-octatriene-1-oic acid and 2,4,6-octatriene-1-ol | Giuliani S.p.A. (IT) | 2010-10-20 | — | — | EP | disclosed |
| EP-2241543-A1 | Process for the preparation of 2,4,6-octatriene-1-oic acid and 2,4,6-octatriene-1-ol | Giuliani S.p.A. (IT) | 2010-10-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022282-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-OCTATRIENE-1-OIC ACID AND 2,4,6-OCTATRIENE-1-OL | OSTC, APEH, OXER1 | TSHR 875/4885TP53 4545/4885EGLN1 1781/4885 |
| US-20160213635-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | PKLR, AKR1C3, HK1 | TSHR 3804/4885TP53 111/4885EGLN1 1755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.