SCHEMBL4167976

SCHEMBL4167976

O=C(O)C1(C(=O)OCC2CCCCC2)CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
SLC1A3 P43003 4/20 0.41
SLC1A2 P43004 4/20 0.41
SLC1A1 P43005 4/20 0.41
THRA P10827 2/20 0.36
THRB P10828 2/20 0.36
SPHK1 Q9NYA1 3/20 0.35
CHRM2 P08172 2/20 0.34
CHRM4 P08173 2/20 0.34
CHRM5 P08912 2/20 0.34
CHRM1 P11229 2/20 0.34
CHRM3 P20309 2/20 0.34
MGLL Q99685 2/20 0.34
ABCB11 O95342 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
DRD1 P21728 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL669713 0.91 LMNA (0.49) LMNASLC1A3SLC1A2SLC1A1THRA
SCHEMBL7993966 0.79 LMNA (0.47) LMNASLC1A3SLC1A2SLC1A1THRA
SCHEMBL1375231 0.78 TP53 (0.45) MGLLCYP3A4
SCHEMBL26939915 0.77 CYP2C19 (0.38) LMNATHRATHRBCHRM2CHRM4
SCHEMBL6943690 0.74 GAA (0.37) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL10850510 0.74 SMN1; SMN2 (0.41) KCNH2CYP2C19
SCHEMBL9806691 0.74 SMN1; SMN2 (0.41) KCNH2CYP2C19
SCHEMBL3780276 0.74 CYP2C19 (0.36) LMNASLC1A3SLC1A2SLC1A1CYP2D6
SCHEMBL670857 0.74 SMN1; SMN2 (0.41) KCNH2CYP2C19
SCHEMBL1066774 0.74 EPHX1 (0.41) LMNACHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7162130-B2 Optical fiber with thermoplastic material based coating PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2007-01-09 US claimed
US-20060127019-A1 Optical fiber with thermoplastic material based coating PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2006-06-15 US claimed
CN-105683272-A Electrically insulating and thermally conductive polymer compositions 纳幕尔杜邦公司 2016-06-15 CN disclosed
US-20090104426-A1 Fibers, Tapes and Films Prepared from Olefinic and Segmented Elastomers E.I. DU PONT DE NEMOURS AND COMPANY 2009-04-23 US disclosed
US-7162130-B2 Optical fiber with thermoplastic material based coating PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2007-01-09 US disclosed
US-20060127019-A1 Optical fiber with thermoplastic material based coating PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2006-06-15 US disclosed
EP-1554226-A1 OPTICAL FIBER WITH THERMOPLASTIC MATERIAL BASED COATING Pirelli & C. S.p.A. (IT) 2005-07-20 EP disclosed
EP-1523590-A1 FIBERS, TAPES AND FILMS PREPARED FROM OLEFINIC AND SEGMENTED ELASTOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2005-04-20 EP disclosed
US-20050031865-A1 Fibers, tapes and films prepared from olefinic and segmented elastomers SEIMI CHEMICAL CO., LTD. (JP) 2005-02-10 US disclosed
WO-2004037739-A1 OPTICAL FIBER WITH THERMOPLASTIC MATERIAL BASED COATING PIRELLI & C. S.P.A. (IT) 2004-05-06 WO disclosed
WO-2004009882-A1 FIBERS, TAPES AND FILMS PREPARED FROM OLEFINIC AND SEGMENTED ELASTOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-01-29 WO disclosed
EP-0906456-B1 ELASTIC FIBRE DSM NV (NL) 2002-01-16 EP disclosed
US-6270896-B1 ELONGATION; STRETCHING DSM N.V. (NL) 2001-08-07 US disclosed