SCHEMBL669713

SCHEMBL669713

O=C(OCC1CCCCC1)C1(C(=O)OCC2CCCCC2)CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
SLC1A3 P43003 4/20 0.41
SLC1A2 P43004 4/20 0.41
SLC1A1 P43005 4/20 0.41
SPHK1 Q9NYA1 4/20 0.37
CYP2C19 P33261 1/20 0.36
PARP15 Q460N3 1/20 0.36
PARP10 Q53GL7 1/20 0.36
CYP3A4 P08684 2/20 0.36
THRA P10827 2/20 0.36
THRB P10828 2/20 0.36
ABCB11 O95342 1/20 0.36
CYP1A2 P05177 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CYP2D6 P10635 1/20 0.36
CHRM1 P11229 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4167976 0.91 LMNA (0.49) LMNASLC1A3SLC1A2SLC1A1SPHK1
SCHEMBL7993966 0.83 LMNA (0.47) LMNASLC1A3SLC1A2SLC1A1SPHK1
SCHEMBL1066774 0.81 EPHX1 (0.41) LMNACYP3A4ABCB11CYP1A2CHRM2
SCHEMBL7993969 0.76 LMNA (0.41) LMNASLC1A3SLC1A2SLC1A1SPHK1
SCHEMBL471872 0.76 TP53 (0.49) LMNACYP3A4TSHRMAPK1
SCHEMBL1669840 0.74 LMNA (0.59) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL5628296 0.73 SLC1A3 (0.37) LMNASLC1A3SLC1A2SLC1A1SPHK1
SCHEMBL23129641 0.73 LMNA (0.57) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL4631096 0.73 LMNA (0.62) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL1864716 0.73 LMNA (0.62) LMNASLC1A3SLC1A2SLC1A1PARP15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3350262-B1 STYRENIC BLOCK COPOLYMER COMPOSITIONS KRATON POLYMERS US LLC (US) 2023-08-16 EP disclosed
US-20210340352-A1 LOW SMOKE HALOGEN FREE FLAME RETARDANT THERMOPLASTIC ELASTOMER COMPOSITIONS CELANESE POLYMERS HOLDING, INC. 2021-11-04 US disclosed
US-11066533-B2 Low smoke halogen free flame retardant thermoplastic elastomer compositions DUPONT POLYMERS. INC. (US) 2021-07-20 US disclosed
US-20190106568-A1 HALOGEN FREE FLAME RETARDANT THERMOPLASTIC ELASTOMER COMPOSITIONS CONTAINING CYCLODEXTRINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2019-04-11 US disclosed
CN-105683272-B Polymer composition electrically insulating but thermally conductive 纳幕尔杜邦公司 2019-02-12 CN disclosed
EP-3436514-A1 HALOGEN FREE FLAME RETARDANT THERMOPLASTIC ELASTOMER COMPOSITIONS CONTAINING CYCLODEXTRINS E. I. du Pont de Nemours and Company (US) 2019-02-06 EP disclosed
EP-3201263-B1 LOW SMOKE HALOGEN FREE FLAME RETARDANT THERMOPLASTIC ELASTOMER COMPOSITIONS DU PONT (US) 2019-01-02 EP disclosed
US-10066098-B2 Styrenic block copolymer compositions KRATON POLYMERS U.S. LLC (US) 2018-09-04 US disclosed
EP-3350262-A1 STYRENIC BLOCK COPOLYMER COMPOSITIONS Kraton Polymers U.S. LLC (US) 2018-07-25 EP disclosed
CN-107840908-A A kind of ingredient of solid catalyst, catalyst system and pre-polymerized catalyst for olefinic polymerization 中国石油化工股份有限公司 2018-03-27 CN disclosed
US-8415415-B2 Heat stable halogen-free flame retardant copolyester thermoplastic elastomer compositions E I DU PONT DE NEMOURS AND COMPANY (US) 2013-04-09 US disclosed
CN-102906167-A Process for enhancing compression set resistance of foamed copolyester compositions DU PONT 2013-01-30 CN disclosed
WO-2012119057-A1 LOW SMOKE HALOGEN FREE FLAME RETARDANT THERMOPLASTIC ELASTOMER COMPOSITIONS CONTAINING ZEOLITES E. I. DUPONT DE NEMOURS AND COMPANY (US) 2012-09-07 WO disclosed
US-20120224818-A1 LOW SMOKE HALOGEN FREE FLAME RETARDANT THERMOPLASTIC ELASTOMER COMPOSITIONS CONTAINING ZEOLITES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-09-06 US disclosed
US-20120211256-A1 HEAT STABLE HALOGEN-FREE FLAME RETARDANT COPOLYESTER THERMOPLASTIC ELASTOMER COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-08-23 US disclosed
WO-2012109457-A1 POLYESTER COMPOSITIONS WITH IMPROVED PROPERTIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-08-16 WO disclosed
US-20120201986-A1 POLYESTER COMPOSITIONS WITH IMPROVED PROPERTIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-08-09 US disclosed
US-20120128911-A1 SOLID STATE POLYMERIZATIONS OF POLYESTER E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-24 US disclosed
US-20120098158-A1 PROCESS FOR ENHANCING COMPRESSION SET RESISTANCE OF FOAMED COPOLYESTER COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-04-26 US disclosed
WO-2012024280-A1 HEAT STABLE HALOGEN-FREE FLAME RETARDANT COPOLYESTER THERMOPLASTIC ELASTOMER COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-02-23 WO disclosed