Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | KCNH3 | Q9ULD8 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28270197 | 1.00 | ALDH1A1 (0.70) | ALDH1A1MAPTKCNH3KDM4EGAA | |
| SCHEMBL6931598 | 0.98 | ALDH1A1 (0.67) | ALDH1A1MAPTKCNH3KDM4EGAA | |
| SCHEMBL10775174 | 0.98 | ALDH1A1 (0.67) | ALDH1A1MAPTKCNH3KDM4EGAA | |
| SCHEMBL16297292 | 0.98 | ALDH1A1 (0.67) | ALDH1A1MAPTKCNH3KDM4EGAA | |
| SCHEMBL9810066 | 0.98 | ALDH1A1 (0.67) | ALDH1A1MAPTKCNH3KDM4EGAA | |
| SCHEMBL26906 | 0.93 | ALDH1A1 (0.73) | ALDH1A1MAPTKCNH3KDM4EGAA | |
| SCHEMBL7776469 | 0.91 | ALDH1A1 (0.70) | ALDH1A1MAPTKCNH3KDM4EGAA | |
| Hydrochloric Acid SCHEMBL16987 | 0.91 | ALDH1A1 (0.70) | ALDH1A1MAPTKCNH3KDM4EGAA | |
| SCHEMBL27928250 | 0.91 | ALDH1A1 (0.70) | ALDH1A1MAPTKCNH3KDM4EGAA | |
| Ammonia Solution, Strong SCHEMBL27928249 | 0.91 | ALDH1A1 (0.70) | ALDH1A1MAPTKCNH3KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109172825-A | A kind of pH and the double response type nano containers of redox and preparation method thereof | 南京理工大学 | 2019-01-11 | — | — | CN | claimed |
| CN-109776618-B | Metal complex and preparation method and application thereof | 池州学院 | 2021-11-19 | — | — | CN | disclosed |
| CN-109172825-A | A kind of pH and the double response type nano containers of redox and preparation method thereof | 南京理工大学 | 2019-01-11 | — | — | CN | disclosed |
| US-9745332-B2 | Catalysts and processes for the hydrogenation of amides | THE GOVERNORS OF THE UNIVERITY OF ALBERTA (CA) | 2017-08-29 | — | — | US | disclosed |
| US-9745332-B2 | Catalysts and processes for the hydrogenation of amides | THE GOVERNORS OF THE UNIVERITY OF ALBERTA (CA) | 2017-08-29 | — | — | US | disclosed |
| US-9745332-B2 | Catalysts and processes for the hydrogenation of amides | THE GOVERNORS OF THE UNIVERITY OF ALBERTA (CA) | 2017-08-29 | — | — | US | disclosed |
| US-20160362372-A1 | PRO-NEUROGENIC COMPOUNDS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2016-12-15 | — | — | US | disclosed |
| US-9446042-B2 | Pro-neurogenic compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-09-20 | — | — | US | disclosed |
| US-9162980-B2 | Anti-depression compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-10-20 | — | — | US | disclosed |
| US-20150290195-A1 | PRO-NEUROGENIC COMPOUNDS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2015-10-15 | — | — | US | disclosed |
| EP-0919554-A1 | IMIDAZOLE-SUBSTITUTED QUINOXALINEDIONE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5518844-A | Method of processing a photosensitive material and photosensitive material processor | FUJI PHOTO FILM CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| US-5457105-A | anticancer use; e.g. 4-(3'-chloro-4'-fluoroanilino)-6,7-dimethoxyquinazoline (gefitinib) | ZENECA LIMITED (GB) | 1995-10-10 | — | — | US | disclosed |
| EP-0566226-A1 | Quinazoline derivatives | ZENECA LIMITED (GB) | 1993-10-20 | — | — | EP | disclosed |
| US-5176987-A | N-/Hydroxyalkyl/-P-Phenylenediamine Developer | FUJI PHOTO FILM CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| US-5166344-A | Process for the preparation of imidazoquinoxalinones | BERLEX LABORATORIES, INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5055465-A | IMIDAZOQUINOXALINONES, THEIR AZA ANALOGS AND PROCESS FOR THEIR PREPARATION | BERLEX LABORATORIES, INC. (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0400583-A1 | Imidazoquinoxalinones, their aza analogs and process for their preparation | BERLEX LABORATORIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0188846-B1 | CRYSTALLINE UNSATURATED POLYESTER AND THE PREPARATION THEREOF | DSM RESINS B.V. (NL) | 1989-07-26 | — | — | EP | disclosed |
| US-4839438-A | POLYESTERURETHANE COPOLYMERS | DSM RESINS B.V. (NL) | 1989-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150290195-A1 | PRO-NEUROGENIC COMPOUNDS | DCX, GAP43, BDNF | ALDH1A1 1654/4885MAPT 559/4885KCNH3 1589/4885 |
| US-20160362372-A1 | PRO-NEUROGENIC COMPOUNDS | DCX, GAP43, BDNF | ALDH1A1 1654/4885MAPT 559/4885KCNH3 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.