Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.53 |
| ▸ | CALML3 | P27482 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SDHA | P31040 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4168449 | 1.00 | MAOA (0.53) | MAOAF10CALML3CYP2C19CYP3A4 | |
| SCHEMBL4173660 | 0.92 | MAOA (0.63) | MAOAF10CALML3CYP2C19CYP3A4 | |
| SCHEMBL4173652 | 0.92 | MAOA (0.63) | MAOAF10CALML3CYP2C19CYP3A4 | |
| SCHEMBL4163619 | 0.91 | MAOA (0.54) | MAOAF10CALML3CYP2C19CYP3A4 | |
| SCHEMBL4163622 | 0.91 | MAOA (0.54) | MAOAF10CALML3CYP2C19CYP3A4 | |
| SCHEMBL4181421 | 0.91 | F10 (0.55) | MAOAF10CALML3CYP2C19CYP3A4 | |
| SCHEMBL4181426 | 0.91 | F10 (0.55) | MAOAF10CALML3CYP2C19CYP3A4 | |
| SCHEMBL4174220 | 0.91 | F10 (0.54) | MAOAF10CALML3CYP2C19CYP3A4 | |
| SCHEMBL4174223 | 0.91 | F10 (0.54) | MAOAF10CALML3CYP2C19CYP3A4 | |
| SCHEMBL4168134 | 0.90 | MAOA (0.58) | MAOAF10CALML3CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018123-A1 | Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation | SINDKHEDKAR MILIND D | 2009-01-15 | — | — | US | claimed |
| EP-1912980-A2 | OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION | Wockhardt Limited (IN) | 2008-04-23 | — | — | EP | claimed |
| WO-2007023507-A2 | OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION | WOCKHARDT LIMITED (IN) | 2007-03-01 | — | — | WO | claimed |
| US-20090018123-A1 | Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation | SINDKHEDKAR MILIND D | 2009-01-15 | — | — | US | disclosed |
| US-20090018123-A1 | Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation | SINDKHEDKAR MILIND D | 2009-01-15 | — | — | US | disclosed |
| US-20090018123-A1 | Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation | SINDKHEDKAR MILIND D | 2009-01-15 | — | — | US | disclosed |
| EP-1912980-A2 | OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION | Wockhardt Limited (IN) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007023507-A2 | OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION | WOCKHARDT LIMITED (IN) | 2007-03-01 | — | — | WO | disclosed |
| WO-2007023507-A2 | OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION | WOCKHARDT LIMITED (IN) | 2007-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018123-A1 | Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation | POLL, POLM, POLRMT | MAOA 3788/4885F10 2299/4885CALML3 4576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.