SCHEMBL4168622

SCHEMBL4168622

O=C(O)C=CC(=O)Oc1cccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.53
KDM4E B2RXH2 4/20 0.53
HPGD P15428 3/20 0.53
MAPT P10636 2/20 0.53
ALDH1A1 P00352 4/20 0.53
PGR P06401 1/20 0.53
GAA P10253 1/20 0.53
PTGS1 P23219 1/20 0.53
MAPK1 P28482 1/20 0.53
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
RAB9A P51151 1/20 0.51
TDP1 Q9NUW8 1/20 0.50
FABP3 P05413 5/20 0.48
FABP7 O15540 4/20 0.48
FABP5 Q01469 3/20 0.48
HTT P42858 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4168618 1.00 HSD17B10 (0.53) HSD17B10KDM4EHPGDMAPTALDH1A1
SCHEMBL11040570 0.93 HSD17B10 (0.59) HSD17B10KDM4EHPGDMAPTALDH1A1
SCHEMBL2834574 0.93 HSD17B10 (0.59) HSD17B10KDM4EHPGDMAPTALDH1A1
SCHEMBL10707682 0.93 HSD17B10 (0.59) HSD17B10KDM4EHPGDMAPTALDH1A1
SCHEMBL28796708 0.84 HSD17B10 (0.50) HSD17B10KDM4EHPGDMAPTALDH1A1
SCHEMBL1157729 0.84 ESR1 (0.74) HSD17B10KDM4EHPGDMAPTALDH1A1
SCHEMBL1157727 0.84 ESR1 (0.74) HSD17B10KDM4EHPGDMAPTALDH1A1
SCHEMBL1338970 0.83 HSD17B10 (0.57) HSD17B10KDM4EHPGDMAPTALDH1A1
SCHEMBL1338968 0.83 HSD17B10 (0.57) HSD17B10KDM4EHPGDMAPTALDH1A1
SCHEMBL331725 0.83 HSD17B10 (0.49) HSD17B10KDM4EHPGDMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090247680-A1 ADHESION PROMOTING ADDITIVE AVERY DENNISON CORPORATION (US) 2009-10-01 US disclosed
EP-2024440-A2 ADHESION PROMOTING ADDITIVE AVERY DENNISON CORPORATION (US) 2009-02-18 EP disclosed
WO-2007146603-A2 ADHESION PROMOTING ADDITIVE AVERY DENNISON CORPORATION (US) 2007-12-21 WO disclosed
EP-0140530-B1 LATENTLY-CURABLE ORGANOSILICONE RELEASE COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP disclosed
US-4533575-A ETHYLENICALLY UNSATURATED POLYSILOXANE AND POLYHYDROSILOXANE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-08-06 US disclosed
EP-0140530-A1 Latently-curable organosilicone release coating composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-08 EP disclosed
US-4504645-A GELATION INHIBITION USING A MONOESTER OR -AMIDE OF AN UNSATURATED DICARBOXYLIC ACID; SHELF LIFE; HEAT CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-12 US disclosed
US-4427820-A STYRENE, MALEIC ACID DERIVATIVE, EMULSION POLYMERIZATION IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-24 US disclosed