Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CETP | P11597 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | UBE2N | P61088 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27970625 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL27612145 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL29879550 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL8517654 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL3730643 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL4169780 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL751283 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL8652229 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL17501649 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL27243094 | 0.97 | SPHK1 (0.58) | SPHK1CYP2D6LMNAGMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040197416-A1 | Nanocapsules containing a steroid for cosmetic compositions | L'OREAL (FR) | 2004-10-07 | — | — | US | claimed |
| US-6486147-B2 | FOR PREVENTING OR TREATING CHRONOLOGICAL OR ACTINIC AGEING OF SKIN | L'OREAL (FR) | 2002-11-26 | — | — | US | claimed |
| EP-1092422-B1 | Composition, particularly for cosmetics containing a sapogenin | OREAL (FR) | 2002-06-26 | — | — | EP | claimed |
| US-6391287-B1 | STORAGE STABLE COMPOSITIONS | L'OREAL (FR) | 2002-05-21 | — | — | US | claimed |
| US-20020028186-A1 | Composition containing sapogenin | L'OREAL (FR) | 2002-03-07 | — | — | US | claimed |
| US-20010044430-A1 | Cosmetic composition containing a steroid and a 2-alkylalkanol or an ester thereof | L'OREAL (FR) | 2001-11-22 | — | — | US | claimed |
| US-6294157-B1 | AND A SOLUBILIZING SYSTEM COMPRISING: (A) NON-EMULSIFYING ESTER OF A FATTY ACID AND/OR OF A FATTY ALCOHOL, OR A PLANT OIL, AND (B) AT LEAST ONE BRANCHED FATTY ALCOHOL WHOSE HYDROCARBON-BASED CHAIN CONTAINS AT LEAST 8 CARBON ATOMS, | L'OREAL (FR) | 2001-09-25 | — | — | US | claimed |
| US-20250177332-A1 | PHARMACEUTICAL DOSAGE FORM OF LACOSAMIDE | SHANGHAI AUCTA PHARMACEUTICALS CO., LTD. (CN) | 2025-06-05 | — | — | US | disclosed |
| US-20200352892-A1 | TOPICAL FOAM COMPOSITION | MAYNE PHARMA LLC (US) | 2020-11-12 | — | — | US | disclosed |
| US-10688071-B2 | Topical foam composition | MAYNE PHARMA LLC (US) | 2020-06-23 | — | — | US | disclosed |
| US-10568859-B2 | Topical foam composition | MAYNE PHARMA LLC (US) | 2020-02-25 | — | — | US | disclosed |
| CN-109528532-A | A kind of skin care item and preparation method thereof containing choline vanillate | 珠海中科先进技术研究院有限公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-106668818-A | Herbal curing cream | 王亮 | 2017-05-17 | — | — | CN | disclosed |
| US-6391287-B1 | STORAGE STABLE COMPOSITIONS | L'OREAL (FR) | 2002-05-21 | — | — | US | disclosed |
| US-20020055562-A1 | Gel compositions | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2002-05-09 | — | — | US | disclosed |
| US-20020028186-A1 | Composition containing sapogenin | L'OREAL (FR) | 2002-03-07 | — | — | US | disclosed |
| US-20010044430-A1 | Cosmetic composition containing a steroid and a 2-alkylalkanol or an ester thereof | L'OREAL (FR) | 2001-11-22 | — | — | US | disclosed |
| EP-1141111-A1 | GEL COMPOSITIONS | Penreco (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6294157-B1 | AND A SOLUBILIZING SYSTEM COMPRISING: (A) NON-EMULSIFYING ESTER OF A FATTY ACID AND/OR OF A FATTY ALCOHOL, OR A PLANT OIL, AND (B) AT LEAST ONE BRANCHED FATTY ALCOHOL WHOSE HYDROCARBON-BASED CHAIN CONTAINS AT LEAST 8 CARBON ATOMS, | L'OREAL (FR) | 2001-09-25 | — | — | US | disclosed |
| WO-2000026285-A1 | GEL COMPOSITIONS | PENRECO (US) | 2000-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040197416-A1 | Nanocapsules containing a steroid for cosmetic compositions | NR5A1, CYP17A1, CYP11A1 | SPHK1 459/4885CYP2D6 408/4885LMNA 2342/4885 |
| US-20010044430-A1 | Cosmetic composition containing a steroid and a 2-alkylalkanol or an ester thereof | NOTUM, HSD3B2, HSD3B1 | SPHK1 455/4885CYP2D6 669/4885LMNA 1207/4885 |
| US-20020028186-A1 | Composition containing sapogenin | CYP46A1, FASN, ASAH2 | SPHK1 595/4885CYP2D6 643/4885LMNA 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.