SCHEMBL4170262

SCHEMBL4170262

NCC(=O)N(C(=O)CN)[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28330169 0.90 ALOX15 (0.38) ALOX15BLMPMP22KMT2A
SCHEMBL4032761 0.85 ALOX15 (0.44) ALOX15BLMPMP22KMT2A
SCHEMBL27916807 0.83 KMT2A (0.35) ALOX15BLMPMP22KMT2A
SCHEMBL11133657 0.83 ALOX15 (0.42) ALOX15BLMPMP22KMT2A
SCHEMBL11222164 0.82 KMT2A (0.50) ALOX15BLMPMP22KMT2A
SCHEMBL11222161 0.82 KMT2A (0.50) ALOX15BLMPMP22KMT2A
SCHEMBL23878704 0.81 KMT2A (0.42) ALOX15BLMPMP22KMT2A
SCHEMBL29140275 0.81 ALOX15 (0.42) ALOX15BLMPMP22KMT2A
SCHEMBL4299640 0.77 GSR (0.48) ALOX15BLMKMT2A
SCHEMBL4299915 0.77 GSR (0.48) ALOX15BLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107857795-A The preparation method of glycylglutamine impurity 山东齐都药业有限公司 2018-03-30 CN disclosed
US-20090176743-A1 Methods for treating or preventing reactivation of a latent herpesvirus infection BETH ISRAEL DEACONESS MEDICAL CENTER 2009-07-09 US disclosed
WO-2007016450-A2 METHODS FOR TREATING OR PREVENTING REACTIVATION OF A LATENT HERPESVIRUS INFECTION BETH ISRAEL DEACONESS MEDICAL CENTER (US) 2007-02-08 WO disclosed
EP-0833644-B1 PHARMACEUTICAL AND DIET FORMULATIONS FOR THE PROPHYLAXIS AND TREATMENT OF GASTROINTESTINAL DISORDERS BRACCO SPA (IT) 2003-03-19 EP disclosed
CN-1082373-C Pharmaceutical and dietary preparation for preventing and treating gastrointestinal diseases BRACCO SPA (IT) 2002-04-10 CN disclosed
US-6007808-A NUTRIENT MIXTURE OF EUBIOTIC BACTERIA AND GLUTAMINE OR GLUTAMINE-CONTAINING POLYPEPTIDE DIBRA S.P.A. (IT) 1999-12-28 US disclosed
CN-1188413-A Pharmaceutical and diet formulations for prophylaxis and treatment of gastrointestinal disorders BRACCO SPA (IT) 1998-07-22 CN disclosed
EP-0833644-A1 PHARMACEUTICAL AND DIET FORMULATIONS FOR THE PROPHYLAXIS AND TREATMENT OF GASTROINTESTINAL DISORDERS BRACCO S.p.A. (IT) 1998-04-08 EP disclosed
WO-1997000688-A1 PHARMACEUTICAL AND DIET FORMULATIONS FOR THE PROPHYLAXIS AND TREATMENT OF GASTROINTESTINAL DISORDERS BRACCO S.P.A. (IT) 1997-01-09 WO disclosed