SCHEMBL4299915

SCHEMBL4299915

NCCCC[C@@H](C(=O)O)N(C(=O)CN)C(=O)CN

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.48
RNPEP Q9H4A4 1/20 0.47
CPB2 Q96IY4 8/20 0.43
FOLH1 Q04609 1/20 0.38
CYP2D6 P10635 1/20 0.35
NFKB1 P19838 1/20 0.35
BLM P54132 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PLG P00747 1/20 0.34
LMNA P02545 1/20 0.34
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.34
SLC6A2 P23975 1/20 0.34
RECQL P46063 1/20 0.34
SLC6A3 Q01959 1/20 0.34
KMT2A Q03164 1/20 0.34
CPB1 P15086 1/20 0.34
GABRR1 P24046 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4299640 1.00 GSR (0.48) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL27731517 0.90 CPB2 (0.44) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL27731516 0.90 CPB2 (0.44) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL2887202 0.87 GSR (0.53) GSRRNPEPCPB2
SCHEMBL22442197 0.85 GSR (0.46) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL22442198 0.85 GSR (0.46) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL22442204 0.85 GSR (0.46) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL22442180 0.85 GSR (0.46) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL7587435 0.85 GSR (0.46) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL4180146 0.85 GSR (0.46) GSRRNPEPCPB2FOLH1GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9868781-B2 Antibodies for ubiquitinated proteins CORNELL UNIVERSITY (US) 2018-01-16 US disclosed
US-20090317409-A1 Antibodies for ubiquitinated proteins CORNELL RESEARCH FOUNDATION, INC. (US) 2009-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090317409-A1 Antibodies for ubiquitinated proteins UBQLN1, STUB1, UBAP2 GSR 4284/4885RNPEP 361/4885CPB2 1238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.