SCHEMBL417048

SCHEMBL417048

C[Si](C)(CCC1CC2C=CC1C2)OCC1CC2C=CC1C2

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.37
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HTT P42858 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17772766 0.92 ALDH1A1 (0.35) KDM4EALDH1A1MEN1KMT2A
SCHEMBL6063180 0.90 KDM4E (0.41) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL12910915 0.88 ALDH1A1 (0.34) KDM4EALDH1A1MEN1KMT2A
SCHEMBL22957994 0.88 ALDH1A1 (0.34) KDM4EALDH1A1MEN1KMT2A
SCHEMBL17775092 0.88 ALDH1A1 (0.34) KDM4EALDH1A1MEN1KMT2A
SCHEMBL12910925 0.85 ALDH1A1 (0.34) KDM4EALDH1A1
SCHEMBL23911750 0.85 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL416791 0.85 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL12910916 0.84 KDM4E (0.33) KDM4EALDH1A1
SCHEMBL1760598 0.83 KDM4E (0.39) KDM4EALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420293-B2 Optical waveguides and methods thereof SUMITOMO BAKELITE CO., LTD. (JP) 2013-04-16 US disclosed
US-8420293-B2 Optical waveguides and methods thereof SUMITOMO BAKELITE CO., LTD. (JP) 2013-04-16 US disclosed
US-8200058-B2 Light guide and light guide structure SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-06-12 US disclosed
US-20120064458-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF PROMERUS, LLC (US) 2012-03-15 US disclosed
US-8053166-B2 Optical waveguides and methods thereof SUMITOMO BAKELITE CO. LTD. (JP) 2011-11-08 US disclosed
US-8021825-B2 Optical waveguides and methods thereof SUMITOMO BAKELITE CO., LTD. (JP) 2011-09-20 US disclosed
US-7820356-B2 photo-induced thermally developable film comprising norbornene-type polyalkenamer copolymer and a procatalyst; curable; transparent or colorless, and propagation loss SUMITOMO BAKELITE CO. LTD. (JP) 2010-10-26 US disclosed
US-20100067861-A1 LIGHT GUIDE AND LIGHT GUIDE STRUCTURE SUMITOMO BAKELITE COMPANY LIMITED (JP) 2010-03-18 US disclosed
US-20100061688-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2010-03-11 US disclosed
US-20100062378-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2010-03-11 US disclosed
US-20070148566-A1 Optical waveguides and methods thereof SUMITOMO BAKELITE CO., LTD. (JP) 2007-06-28 US disclosed