SCHEMBL416791

SCHEMBL416791

C[Si](C)(CCC1CC2C=CC1C2)O[Si](C)(C)CCC1CC2C=CC1C2

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.40
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
HTT P42858 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23911750 1.00 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL4401258 0.93 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL1221875 0.93 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL7526586 0.93 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL16418948 0.92 ALDH1A1 (0.36) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL4403500 0.89 ALDH1A1 (0.35) KDM4EALDH1A1MEN1KMT2A
SCHEMBL29325829 0.89 ALDH1A1 (0.36) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL1760598 0.88 KDM4E (0.39) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL29326128 0.88 ALDH1A1 (0.35) KDM4EALDH1A1MEN1KMT2A
SCHEMBL29326145 0.88 ALDH1A1 (0.35) KDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12180385-B2 Shelf life stable and improved mass polymerizable polycyclic-olefinic compositions PROMERYS, LLC (US) 2024-12-31 US claimed
EP-4437027-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2024-10-02 EP claimed
US-11845880-B2 Polycyclic-olefinic compositions for low-loss films having improved thermal properties PROMERUS, LLC (US) 2023-12-19 US claimed
US-11795285-B2 Dual UV blockers containing stable photoactive mass polymerizable polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2023-10-24 US claimed
EP-4237460-A1 POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES Promerus, LLC (US) 2023-09-06 EP claimed
EP-4237461-A1 SHELF LIFE STABLE AND IMPROVED MASS POLYMERIZABLE POLYCYCLIC-OLEFINIC COMPOSITIONS Promerus, LLC (US) 2023-09-06 EP claimed
US-11697744-B2 High impact strength 3D printing materials derived from polycycloolefin monomers and crosslinkers PROMERUS, LLC (US) 2023-07-11 US claimed
WO-2023097092-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2023-06-01 WO claimed
US-20230167256-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2023-06-01 US claimed
WO-2022094232-A1 POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES PROMERUS, LLC (US) 2022-05-05 WO claimed
US-11186731-B2 Slippery self-lubricating polymer surfaces PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2021-11-30 US claimed
US-11142662-B2 High impact strength 3D printing materials derived from polycycloolefin monomers and crosslinkers PROMERUS, LLC (US) 2021-10-12 US claimed
US-20200199391-A1 HIGH IMPACT STRENGTH 3D PRINTING MATERIALS DERIVED FROM POLYCYCLOOLEFIN MONOMERS AND CROSSLINKERS PROMERUS, LLC (US) 2020-06-25 US claimed
WO-2020132665-A1 HIGH IMPACT STRENGTH 3D PRINTING MATERIALS DERIVED FROM POLYCYCOOLEFIN MONOMERS AND CROSSLINKERS PROMERUS, LLC (US) 2020-06-25 WO claimed
US-20180327608-A1 SLIPPERY SELF-LUBRICATING POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2018-11-15 US claimed
US-9587147-B2 Pressure-sensitive adhesive compositions, polarizers and liquid crystal displays comprising the same LG CHEM, LTD. (KR) 2017-03-07 US claimed
EP-2230287-B1 PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS, POLARIZERS AND LIQUID CRYSTAL DISPLAYS COMPRISING THE SAME LG CHEMICAL LTD (KR) 2013-06-12 EP claimed
US-20110032455-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS, POLARIZERS AND LIQUID CRYSTAL DISPLAYS COMPRISING THE SAME LG CHEM, LTD. (KR) 2011-02-10 US claimed
EP-2230287-A2 PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS, POLARIZERS AND LIQUID CRYSTAL DISPLAYS COMPRISING THE SAME LG Chem, Ltd. (KR) 2010-09-22 EP claimed
US-20030208016-A1 Radical polymerizable compositions containing polycyclic olefins HENKEL LOCTITE CORPORATION 2003-11-06 US claimed