Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4165967 | 0.85 | KDM4E (0.42) | NPC1RAB9AALDH1A1L3MBTL1CYP3A4 | |
| Bromide SCHEMBL4880840 | 0.84 | CYP3A4 (0.41) | NPC1RAB9AALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL4169299 | 0.83 | SMN1; SMN2 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5254676 | 0.80 | CYP3A4 (0.39) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL4163641 | 0.80 | CYP3A4 (0.49) | KMT2ANPC1RAB9AALDH1A1CYP3A4 | |
| Bromide SCHEMBL7554050 | 0.79 | CYP3A4 (0.48) | KMT2ANPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL4654873 | 0.77 | ALDH1A1 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6219463 | 0.75 | CYP3A4 (0.47) | NPC1RAB9ACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL2368041 | 0.74 | CYP3A4 (0.68) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL5261078 | 0.72 | CYP3A4 (0.34) | NPC1RAB9AALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060063797-A1 | Process for preparing a substituted imidazopyridine compound | ELMAN BJORN | 2006-03-23 | — | — | US | claimed |
| EP-3481827-B1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USE THEREOF | JEIL PHARMACEUTICAL CO LTD (KR) | 2021-11-03 | — | — | EP | disclosed |
| US-10696671-B2 | Imidazo[1,2-A]pyridine derivatives, methods for preparing the same and use thereof | JEIL PHARMACEUTICAL CO., LTD. (KR) | 2020-06-30 | — | — | US | disclosed |
| US-20190152971-A1 | Imidazo[1,2-A]Pyridine Derivatives, Methods for Preparing the Same and Use Thereof | JEIL PHARMACEUTICAL CO., LTD. (KR) | 2019-05-23 | — | — | US | disclosed |
| EP-3481827-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USE THEREOF | Jeil Pharmaceutical Co., Ltd. (KR) | 2019-05-15 | — | — | EP | disclosed |
| WO-2018008929-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USE THEREOF | JEIL PHARMACEUTICAL CO.,LTD. (KR) | 2018-01-11 | — | — | WO | disclosed |
| US-20090291977-A1 | Chromane Derivatives Useful As Acid Pump Antagonists | RAQUALIA PHARMA INC. (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090247755-A1 | Process for Preparing a Substituted Imidazopyridine Compound | ELMAN BJORN | 2009-10-01 | — | — | US | disclosed |
| US-20090247755-A1 | Process for Preparing a Substituted Imidazopyridine Compound | ELMAN BJORN | 2009-10-01 | — | — | US | disclosed |
| US-20090247755-A1 | Process for Preparing a Substituted Imidazopyridine Compound | ELMAN BJORN | 2009-10-01 | — | — | US | disclosed |
| EP-1838309-B1 | CHROMANE DERIVATIVES USEFUL AS ACID PUMP ANTAGONISTS | PFIZER (US) | 2008-08-20 | — | — | EP | disclosed |
| EP-1838309-A1 | CHROMANE DERIVATIVES USEFUL AS ACID PUMP ANTAGONISTS | Pfizer, Inc. (US) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006064339-A1 | CHROMANE DERIVATIVES USEFUL AS ACID PUMP ANTAGONISTS | PFIZER JAPAN INC. (JP) | 2006-06-22 | — | — | WO | disclosed |
| US-20060063797-A1 | Process for preparing a substituted imidazopyridine compound | ELMAN BJORN | 2006-03-23 | — | — | US | disclosed |
| US-6900324-B2 | Process for preparing a substituted imidazopyridine compound | ASTRAZENECA AB (SE) | 2005-05-31 | — | — | US | disclosed |
| EP-1317455-B9 | PROCESS FOR PREPARING A SUBSTITUTED IMIDAZOPYRIDINE COMPOUND | ASTRAZENECA AB (SE) | 2004-11-17 | — | — | EP | disclosed |
| EP-1317455-B1 | PROCESS FOR PREPARING A SUBSTITUTED IMIDAZOPYRIDINE COMPOUND | ASTRAZENECA AB (SE) | 2004-08-04 | — | — | EP | disclosed |
| US-20040039013-A1 | Process for preparing a substituted imidazopyridine compound | ASTRAZENECA AB (SE) | 2004-02-26 | — | — | US | disclosed |
| EP-1317455-A1 | PROCESS FOR PREPARING A SUBSTITUTED IMIDAZOPYRIDINE COMPOUND | AstraZeneca AB (SE) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020523-A1 | PROCESS FOR PREPARING A SUBSTITUTED IMIDAZOPYRIDINE COMPOUND | ASTRAZENECA AB (SE) | 2002-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063797-A1 | Process for preparing a substituted imidazopyridine compound | NISCH, CYP1B1, CYP1A2 | CA12 3749/4885CA1 4005/4885CA2 2860/4885 |
| US-20090247755-A1 | Process for Preparing a Substituted Imidazopyridine Compound | NISCH, CYP1A2, CYP1B1 | CA12 3638/4885CA1 4014/4885CA2 2746/4885 |
| US-20040039013-A1 | Process for preparing a substituted imidazopyridine compound | CYP1B1, BRD1, SKP1 | CA12 4143/4885CA1 3991/4885CA2 2791/4885 |
| US-10696671-B2 | Imidazo[1,2-A]pyridine derivatives, methods for preparing the same and use thereof | HRH2, GIPR, HRH4 | CA12 2800/4885CA1 958/4885CA2 732/4885 |
| US-20090291977-A1 | Chromane Derivatives Useful As Acid Pump Antagonists | HRH2, HRH1, CHRND | CA12 1259/4885CA1 1580/4885CA2 432/4885 |
| US-20190152971-A1 | Imidazo[1,2-A]Pyridine Derivatives, Methods for Preparing the Same and Use Thereof | GIPR, PGC, VIP | CA12 3460/4885CA1 1088/4885CA2 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.