Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4173733 | 1.00 | PRCP (0.44) | PRCPCYP2D6CXCR4CHRNB2CHRNA4 | |
| SCHEMBL4181457 | 1.00 | PRCP (0.44) | PRCPCYP2D6CXCR4CHRNB2CHRNA4 | |
| SCHEMBL20482729 | 1.00 | PRCP (0.44) | PRCPCYP2D6CXCR4CHRNB2CHRNA4 | |
| SCHEMBL4170860 | 1.00 | PRCP (0.44) | PRCPCYP2D6CXCR4CHRNB2CHRNA4 | |
| SCHEMBL13875186 | 1.00 | PRCP (0.44) | PRCPCYP2D6CXCR4CHRNB2CHRNA4 | |
| SCHEMBL4173032 | 0.94 | PRCP (0.44) | PRCPCYP2D6CXCR4 | |
| SCHEMBL4188457 | 0.94 | PRCP (0.44) | PRCPCYP2D6CXCR4 | |
| SCHEMBL4173013 | 0.91 | CHRNB2 (0.43) | PRCPCYP2D6CXCR4CHRNB2CHRNA4 | |
| SCHEMBL5547748 | 0.83 | CXCR4 (0.42) | CYP2D6CXCR4 | |
| SCHEMBL1698200 | 0.72 | KDM4E (0.39) | PRCPCYP2D6CXCR4HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240368146-A1 | Morpholine-Containing & Piperazine-Containing CXCR4 Modulators and Uses Related Thereto | UNIV EMORY (US) | 2024-11-07 | — | — | US | disclosed |
| EP-4373485-A1 | CXCR4 MODULATORS AND USES RELATED THERETO | Emory University (US) | 2024-05-29 | — | — | EP | disclosed |
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | UNIV EMORY (US) | 2023-04-13 | — | — | US | disclosed |
| WO-2023003862-A1 | CXCR4 MODULATORS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2023-01-26 | — | — | WO | disclosed |
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | EMORY UNIVERSITY | 2020-02-20 | — | — | US | disclosed |
| US-20090093454-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2009-04-09 | — | — | US | disclosed |
| US-20090093454-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2009-04-09 | — | — | US | disclosed |
| US-20090093454-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2009-04-09 | — | — | US | disclosed |
| EP-1853604-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006096444-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | PRCP 2259/4885CYP2D6 4404/4885CXCR4 1/4885 |
| US-20240368146-A1 | Morpholine-Containing & Piperazine-Containing CXCR4 Modulators and Uses Related Thereto | CXCR4, CXCL12, MYD88 | PRCP 4184/4885CYP2D6 4666/4885CXCR4 1/4885 |
| US-20090093454-A1 | Chemical Compounds | SLC10A1, CYP11B2, CYP4F3 | PRCP 679/4885CYP2D6 13/4885CXCR4 2681/4885 |
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | PRCP 2259/4885CYP2D6 4404/4885CXCR4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.