Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.61 |
| ▸ | CTSL | P07711 | 1/20 | 0.60 |
| ▸ | CTSB | P07858 | 1/20 | 0.60 |
| ▸ | CTSS | P25774 | 1/20 | 0.60 |
| ▸ | CTSK | P43235 | 1/20 | 0.60 |
| ▸ | KDM1A | O60341 | 9/20 | 0.56 |
| ▸ | MAOA | P21397 | 7/20 | 0.56 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.56 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22034410 | 0.87 | SIRT5 (0.57) | HDAC8 | |
| SCHEMBL22034407 | 0.87 | SIRT5 (0.57) | HDAC8 | |
| SCHEMBL13768104 | 0.83 | CTSL (0.61) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7370634 | 0.83 | HDAC8 (0.73) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL4155113 | 0.83 | KDM1A (0.68) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL4157711 | 0.82 | TACR1 (0.67) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL16999810 | 0.81 | CTSL (0.57) | CTSLCTSBCTSSCTSK | |
| SCHEMBL29360909 | 0.81 | SIRT5 (0.47) | CTSLCTSBCTSSCTSKHDAC8 | |
| SCHEMBL4156354 | 0.80 | HDAC8 (0.60) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL12052836 | 0.79 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080631-A2 | CHEMO-ENZYMATIC SYNTHESIS OF A C-TERMINAL ARYL AMIDE OF AN AMINO ACID OR PEPTIDE | DSM IP ASSETS BV (NL) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080631-A2 | CHEMO-ENZYMATIC SYNTHESIS OF A C-TERMINAL ARYL AMIDE OF AN AMINO ACID OR PEPTIDE | DSM IP ASSETS BV (NL) | 2009-07-02 | — | — | WO | disclosed |