Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | CALML3 | P27482 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172608 | 1.00 | MAOA (0.44) | MAOAMAOBF10CALML3CYP3A4 | |
| SCHEMBL4170100 | 0.88 | MAOA (0.47) | MAOAMAOBF10CALML3CYP3A4 | |
| SCHEMBL4170095 | 0.88 | MAOA (0.47) | MAOAMAOBF10CALML3CYP3A4 | |
| SCHEMBL4170733 | 0.88 | MAOB (0.54) | MAOAMAOBF10CALML3KCNH2 | |
| SCHEMBL4170736 | 0.88 | MAOB (0.54) | MAOAMAOBF10CALML3KCNH2 | |
| SCHEMBL4174146 | 0.85 | MAOA (0.52) | MAOAMAOBF10CALML3 | |
| SCHEMBL4174152 | 0.85 | MAOA (0.52) | MAOAMAOBF10CALML3 | |
| SCHEMBL4169072 | 0.83 | MAOB (0.42) | MAOAMAOBF10CALML3 | |
| SCHEMBL4172629 | 0.83 | MAOA (0.43) | MAOAMAOBF10CALML3 | |
| SCHEMBL4169070 | 0.83 | MAOB (0.42) | MAOAMAOBF10CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018123-A1 | Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation | SINDKHEDKAR MILIND D | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018123-A1 | Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation | POLL, POLM, POLRMT | MAOA 3788/4885MAOB 3240/4885F10 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.