Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.53 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24235513 | 1.00 | KMT2A (0.73) | KMT2AFOLH1TLR2MDM4TP53 | |
| SCHEMBL6575642 | 0.92 | KMT2A (0.64) | KMT2AFOLH1TLR2MDM4TP53 | |
| SCHEMBL22271659 | 0.89 | KMT2A (0.63) | KMT2AFOLH1TLR2MDM2 | |
| SCHEMBL10051914 | 0.89 | KMT2A (0.58) | KMT2AFOLH1TLR2MDM4TP53 | |
| SCHEMBL588932 | 0.89 | KMT2A (0.58) | KMT2AFOLH1TLR2MDM4TP53 | |
| SCHEMBL26512839 | 0.87 | TLR2 (0.61) | KMT2ATLR2MDM2 | |
| SCHEMBL31664707 | 0.87 | KMT2A (0.56) | KMT2AFOLH1TLR2MDM4TP53 | |
| SCHEMBL24728974 | 0.87 | KMT2A (0.56) | KMT2AFOLH1TLR2MDM4TP53 | |
| SCHEMBL17746999 | 0.86 | KMT2A (0.58) | KMT2AFOLH1TLR2MDM4TP53 | |
| SCHEMBL17746997 | 0.86 | KMT2A (0.58) | KMT2AFOLH1TLR2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9539336-B2 | Sialic acid derivatives | BROSSMER REINHARD (DE) | 2017-01-10 | — | — | US | disclosed |
| US-20150174262-A1 | Sialic Acid Derivatives | BROSSMER REINHARD (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20090239939-A1 | Combinations for introducing nucleic acids into cells | PLANK CHRISTIAN | 2009-09-24 | — | — | US | disclosed |
| US-20030026840-A1 | Combinations for introducing nucleic acids into cells | PLANK CHRISTIAN (DE) | 2003-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030026840-A1 | Combinations for introducing nucleic acids into cells | POLRMT, RNASE1, POLI | KMT2A 3522/4885FOLH1 375/4885TLR2 746/4885 |
| US-20150174262-A1 | Sialic Acid Derivatives | NEU1, SIGLEC9, SIGLEC7 | KMT2A 4033/4885FOLH1 1971/4885TLR2 147/4885 |
| US-20090239939-A1 | Combinations for introducing nucleic acids into cells | POLRMT, RNASE1, POLI | KMT2A 3522/4885FOLH1 375/4885TLR2 746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.