Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4171426 | 0.88 | CES1 (0.44) | CES1 | |
| SCHEMBL4173034 | 0.83 | CES1 (0.33) | POLBCES1 | |
| Trifluoroacetic Acid SCHEMBL4169493 | 0.83 | CES1 (0.34) | CES1 | |
| SCHEMBL4159624 | 0.78 | CES1 (0.47) | POLBCES1 | |
| SCHEMBL4606348 | 0.75 | POLB (0.39) | POLBCES1 | |
| Trifluoroacetic Acid SCHEMBL4160625 | 0.75 | CES1 (0.38) | POLBCES1 | |
| SCHEMBL4171428 | 0.71 | CES1 (0.44) | CES1 | |
| SCHEMBL4606140 | 0.71 | CES1 (0.35) | CES1 | |
| Trifluoroacetic Acid SCHEMBL4160622 | 0.71 | PADI4 (0.39) | POLBCES1 | |
| SCHEMBL4166187 | 0.71 | CES1 (0.33) | CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | JONES PHILIP | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | HDAC5, HDAC1, HDAC11 | POLB 1368/4885CES1 1925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.