SCHEMBL4173173

SCHEMBL4173173

C=CC=C(C=Cc1ccccc1)C(=O)C(=C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
LMNA P02545 4/20 0.46
MAPT P10636 3/20 0.46
ALDH1A1 P00352 3/20 0.46
HDAC3 O15379 2/20 0.46
HDAC4 P56524 2/20 0.46
HDAC1 Q13547 2/20 0.46
HDAC2 Q92769 2/20 0.46
HDAC8 Q9BY41 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
PLIN1 O60240 2/20 0.46
RECQL P46063 2/20 0.46
PLIN5 Q00G26 2/20 0.46
ABHD5 Q8WTS1 2/20 0.46
TNKS O95271 1/20 0.46
HCAR2 Q8TDS4 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1336837 0.85 GLA (0.56) GLATDP1LMNAMAPTALDH1A1
SCHEMBL3833463 0.85 GLA (0.49) GLATDP1LMNAMAPTALDH1A1
SCHEMBL3803608 0.82 MAPT (0.53) GLATDP1LMNAMAPTALDH1A1
Methacrylic Acid SCHEMBL3795998 0.79 GLA (0.53) GLATDP1LMNAMAPTALDH1A1
SCHEMBL24603 0.79 MAPT (0.50) GLATDP1LMNAMAPTALDH1A1
Methacrylic Acid SCHEMBL3192490 0.76 TDP1 (0.56) GLATDP1LMNAMAPTALDH1A1
SCHEMBL13639844 0.75 TDP1 (0.47) GLATDP1LMNAMAPTALDH1A1
SCHEMBL25665 0.74 GLA (0.53) GLATDP1LMNAMAPTALDH1A1
SCHEMBL17635458 0.74 TDP1 (0.64) GLATDP1LMNAMAPTALDH1A1
SCHEMBL547750 0.74 TDP1 (0.64) GLATDP1LMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0090950-B1 ROCKET LAUNCHER TUBE Dynamit Nobel Aktiengesellschaft (DE) 1988-06-15 EP claimed
US-4548843-A CELLULOSE ACETATE BUTYRATE, STAINLESS STEEL AND THERMOPLASTIC MATERIAL INOUE MTP KABUSHIKI KAISHA (JP) 1985-10-22 US claimed
EP-0090950-A2 Rocket launcher tube Dynamit Nobel Aktiengesellschaft (DE) 1983-10-12 EP claimed
JP-5304019-B2 2013-10-02 JP disclosed
JP-2009275102-A CIRCUIT CONNECTING MATERIAL HITACHI CHEM CO LTD 2009-11-26 JP disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed
EP-0090950-B1 ROCKET LAUNCHER TUBE Dynamit Nobel Aktiengesellschaft (DE) 1988-06-15 EP disclosed
EP-0087515-B1 PROFILE STRIP, IN PARTICULAR FOR THE PRODUCTION OF WINDOW OR DOOR FRAMES HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1986-02-26 EP disclosed
EP-0087515-A1 Profile strip, in particular for the production of window or door frames HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1983-09-07 EP disclosed