Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.46 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.46 |
| ▸ | F3 | P13726 | 2/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828502 | 0.85 | TDP1 (0.55) | TDP1GLAMAPTLMNAALDH1A1 | |
| SCHEMBL24603 | 0.82 | MAPT (0.50) | TDP1GLAMAPTLMNAALDH1A1 | |
| SCHEMBL21158994 | 0.79 | GLA (0.49) | TDP1GLAMAPTLMNAALDH1A1 | |
| SCHEMBL1336837 | 0.79 | GLA (0.56) | TDP1GLAMAPTLMNAALDH1A1 | |
| SCHEMBL3803608 | 0.78 | MAPT (0.53) | TDP1GLAMAPTLMNAALDH1A1 | |
| SCHEMBL24435651 | 0.76 | F3 (0.56) | TDP1GLAMAPTLMNAALDH1A1 | |
| SCHEMBL13621556 | 0.76 | CES2 (0.43) | MAPTLMNAALDH1A1RECQLCYP1A2 | |
| SCHEMBL4173173 | 0.75 | GLA (0.51) | TDP1GLAMAPTLMNAALDH1A1 | |
| SCHEMBL26636136 | 0.75 | HTT (0.54) | TDP1GLAMAPTALDH1A1HDAC3 | |
| SCHEMBL19872825 | 0.74 | GLA (0.42) | TDP1GLAMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12016312-B2 | Animal models, screening methods, and treatment methods for intraocular diseases or disorders | Smilebiotek Zhuhai Limited (CN) | 2024-06-25 | — | — | US | disclosed |
| US-20220015338-A1 | ANIMAL MODELS, SCREENING METHODS, AND TREATMENT METHODS FOR INTRAOCULAR DISEASES OR DISORDERS | Smilebiotek Zhuhai Limited (CN) | 2022-01-20 | — | — | US | disclosed |
| EP-2520632-A2 | COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE COMPOUND | Cheil Industries Inc. (KR) | 2012-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12016312-B2 | Animal models, screening methods, and treatment methods for intraocular diseases or disorders | MB, MYOC, PDE6A | TDP1 1381/4885GLA 31/4885MAPT 2250/4885 |
| US-20220015338-A1 | ANIMAL MODELS, SCREENING METHODS, AND TREATMENT METHODS FOR INTRAOCULAR DISEASES OR DISORDERS | MB, MYOC, PDE6A | TDP1 1381/4885GLA 31/4885MAPT 2250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.