SCHEMBL3833463

SCHEMBL3833463

C=C(C)C(=O)C(C=Cc1ccccc1)=CC=CC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
LMNA P02545 4/20 0.43
MAPT P10636 3/20 0.43
HDAC3 O15379 3/20 0.43
HDAC4 P56524 3/20 0.43
HDAC1 Q13547 3/20 0.43
HDAC2 Q92769 3/20 0.43
HDAC8 Q9BY41 3/20 0.43
HDAC6 Q9UBN7 3/20 0.43
PLIN1 O60240 2/20 0.43
RECQL P46063 2/20 0.43
PLIN5 Q00G26 2/20 0.43
ABHD5 Q8WTS1 2/20 0.43
HDAC7 Q8WUI4 2/20 0.43
HDAC10 Q969S8 2/20 0.43
HDAC11 Q96DB2 2/20 0.43
HDAC9 Q9UKV0 2/20 0.43
HDAC5 Q9UQL6 2/20 0.43
ALDH1A1 P00352 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4173173 0.85 GLA (0.51) GLATDP1LMNAMAPTHDAC3
Methacrylic Acid SCHEMBL3192490 0.76 TDP1 (0.56) GLATDP1LMNAMAPTHDAC3
SCHEMBL26201152 0.73 GLA (0.43) GLATDP1LMNAMAPTHDAC3
Methacrylic Acid SCHEMBL1533293 0.72 GLA (0.53) GLATDP1LMNAMAPTHDAC3
SCHEMBL547750 0.72 TDP1 (0.64) GLATDP1LMNAMAPTHDAC3
Methacrylic Acid SCHEMBL1005095 0.72 GLA (0.53) GLATDP1LMNAMAPTHDAC3
SCHEMBL17635458 0.72 TDP1 (0.64) GLATDP1LMNAMAPTHDAC3
SCHEMBL19872925 0.71 GLA (0.41) GLATDP1LMNAMAPTHDAC3
SCHEMBL5583505 0.71 LMNA (0.55) GLATDP1LMNAMAPTHDAC3
SCHEMBL17746647 0.70 MAPT (0.50) GLATDP1LMNAMAPTHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1624014-B1 SPECIFIC ACYLATED GLYCEROL COMPOUNDS FOR PLASTICISERS IN POLYMERS AND PROCESS FOR THEIR PREPARATION DANISCO (DK) 2009-10-07 EP disclosed
EP-2011819-A1 Process Danisco A/S (DK) 2009-01-07 EP disclosed
US-20060030654-A1 Composition NIELSEN BJARNE 2006-02-09 US disclosed
EP-1624014-A1 SPECIFIC ACYLATED GYLCEROL COMPOUNDS FOR PLASTICISERS IN POLYMERS AND PROCESS FOR THEIR PREPARATION DANISCO A/S (DK) 2006-02-08 EP disclosed
EP-1218443-B1 SPECIFIC ACYLATED GYLCEROL COMPOUNDS FOR PLASTICISERS IN POLYMERS DANISCO (DK) 2005-10-26 EP disclosed
US-6949597-B2 Composition DANISCO A/S (DK) 2005-09-27 US disclosed
US-20050090590-A1 Composition DUPONT NUTRITION BIOSCIENCES APS (DK) 2005-04-28 US disclosed
US-6734241-B1 THERMOPLASTIC POLYMER AND HYDROPHILIC COMPOUND DANISCO A/S. (DK) 2004-05-11 US disclosed
EP-1218443-A1 SPECIFIC ACYLATED GYLCEROL COMPOUNDS FOR PLASTICISERS IN POLYMERS DANISCO A/S (DK) 2002-07-03 EP disclosed
WO-2001014466-A1 SPECIFIC ACYLATED GYLCEROL COMPOUNDS FOR PLASTICISERS IN POLYMERS DANISCO A/S (DK) 2001-03-01 WO disclosed