Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4171305 | 0.79 | NOD2 (0.50) | HPGDALOX15PDE4DSMN1; SMN2NPC1 | |
| SCHEMBL4167659 | 0.79 | HPGD (0.44) | MAPTHPGDALOX15SMN1; SMN2NPC1 | |
| SCHEMBL4176925 | 0.79 | HPGD (0.44) | MAPTHPGDALOX15PDE4DSMN1; SMN2 | |
| SCHEMBL19769021 | 0.78 | PDE4D (0.46) | MAPTPDE4DPDE4BPDE4APDE4C | |
| SCHEMBL11547093 | 0.78 | HPGD (0.48) | MAPTHPGDALOX15SMN1; SMN2NPC1 | |
| SCHEMBL17208821 | 0.75 | ATR (0.51) | MAPTPDE4DNPC1RAB9APDE4B | |
| SCHEMBL19880454 | 0.75 | PDE4D (0.49) | MAPTPDE4DPDE4BPDE4APDE4C | |
| SCHEMBL71356 | 0.75 | PDE4D (0.47) | MAPTPDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2919282 | 0.75 | HPGD (0.55) | MAPTHPGDALOX15SMN1; SMN2NPC1 | |
| SCHEMBL15958227 | 0.73 | HPGD (0.54) | MAPTHPGDALOX15SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179921-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-26 | — | — | US | disclosed |
| US-20130197029-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-01 | — | — | US | disclosed |
| US-8338443-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-25 | — | — | US | disclosed |
| US-20090118295-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197029-A1 | CHEMICAL COMPOUNDS | MRM1, H1-0, RO60 | MAPT 3827/4885HPGD 4431/4885ALOX15 2783/4885 |
| US-20140179921-A1 | CHEMICAL COMPOUNDS | H1-0, REL, ZYX | MAPT 4018/4885HPGD 4396/4885ALOX15 1886/4885 |
| US-20090118295-A1 | CHEMICAL COMPOUNDS | MRM1, MNS1, CHRM1 | MAPT 4012/4885HPGD 4257/4885ALOX15 2303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.