Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.54 |
| ▸ | RAB9A | P51151 | 11/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11987329 | 0.91 | NPC1 (0.51) | NPC1RAB9AALDH1A1HPGDTP53 | |
| SCHEMBL11987333 | 0.90 | ALDH1A1 (0.58) | NPC1RAB9AALDH1A1HPGDTP53 | |
| SCHEMBL11987338 | 0.89 | NPC1 (0.50) | NPC1RAB9AALDH1A1HPGDTP53 | |
| SCHEMBL11987357 | 0.89 | NPC1 (0.47) | NPC1RAB9AALDH1A1HPGDTP53 | |
| SCHEMBL11987323 | 0.88 | NPC1 (0.59) | NPC1RAB9AALDH1A1HPGDTP53 | |
| SCHEMBL11987324 | 0.86 | RAB9A (0.61) | NPC1RAB9AALDH1A1HPGDTP53 | |
| SCHEMBL11987342 | 0.86 | NPC1 (0.50) | NPC1RAB9AALDH1A1HPGDTP53 | |
| SCHEMBL11987257 | 0.86 | NPC1 (0.46) | NPC1RAB9AALDH1A1HPGDTP53 | |
| SCHEMBL12171105 | 0.85 | NPC1 (0.50) | NPC1RAB9AALDH1A1HPGDTP53 | |
| SCHEMBL11987255 | 0.85 | BACE1 (0.49) | NPC1RAB9AALDH1A1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247087-B2 | Compound having oxadiazole ring structure bonded with aromatic heterocyclic ring and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-08-21 | — | — | US | disclosed |
| US-8247087-B2 | Compound having oxadiazole ring structure bonded with aromatic heterocyclic ring and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-08-21 | — | — | US | disclosed |
| US-8247087-B2 | Compound having oxadiazole ring structure bonded with aromatic heterocyclic ring and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-08-21 | — | — | US | disclosed |
| US-20090230849-A1 | COMPOUND HAVING OXADIAZOLE RING STRUCTURE BONDED WITH AROMATIC HETEROCYCLIC RING AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2009-09-17 | — | — | US | disclosed |
| US-20090230849-A1 | COMPOUND HAVING OXADIAZOLE RING STRUCTURE BONDED WITH AROMATIC HETEROCYCLIC RING AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2009-09-17 | — | — | US | disclosed |
| US-20090230849-A1 | COMPOUND HAVING OXADIAZOLE RING STRUCTURE BONDED WITH AROMATIC HETEROCYCLIC RING AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1932842-A1 | COMPOUND HAVING OXADIAZOLE RING STRUCTURE BONDED WITH AROMATIC HETEROCYCLIC RING AND ORGANIC ELECTROLUMINESCENT DEVICE | Hodogaya Chemical Co., Ltd. (JP) | 2008-06-18 | — | — | EP | disclosed |
| EP-1932842-A1 | COMPOUND HAVING OXADIAZOLE RING STRUCTURE BONDED WITH AROMATIC HETEROCYCLIC RING AND ORGANIC ELECTROLUMINESCENT DEVICE | Hodogaya Chemical Co., Ltd. (JP) | 2008-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090230849-A1 | COMPOUND HAVING OXADIAZOLE RING STRUCTURE BONDED WITH AROMATIC HETEROCYCLIC RING AND ORGANIC ELECTROLUMINESCENT DEVICE | OXA1L, ORC3, OCIAD1 | NPC1 3174/4885RAB9A 4215/4885ALDH1A1 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.