Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4169814 | 0.88 | LMNA (0.33) | LMNAPOLBPIK3C3 | |
| SCHEMBL4172261 | 0.84 | LMNA (0.34) | LMNAPOLBSOS1NR3C1PIK3C3 | |
| SCHEMBL4173836 | 0.78 | — | — | |
| SCHEMBL4172257 | 0.75 | LMNA (0.33) | LMNAPOLBPIK3C3 | |
| SCHEMBL4173832 | 0.75 | LMNA (0.36) | LMNAPOLBPIK3C3 | |
| SCHEMBL4165784 | 0.74 | — | — | |
| SCHEMBL4173371 | 0.73 | PIK3C3 (0.32) | LMNAPOLBPIK3C3 | |
| SCHEMBL4169667 | 0.68 | — | — | |
| SCHEMBL2737292 | 0.67 | GAA (0.38) | LMNAPOLBSOS1NR3C1 | |
| SCHEMBL23888997 | 0.65 | GAA (0.36) | LMNAPOLBSOS1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048112-A1 | Novel Herbicides | SYNGENTA LIMITED (GB) | 2009-02-19 | — | — | US | disclosed |
| US-20090048112-A1 | Novel Herbicides | SYNGENTA LIMITED (GB) | 2009-02-19 | — | — | US | disclosed |
| US-20090048112-A1 | Novel Herbicides | SYNGENTA LIMITED (GB) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048112-A1 | Novel Herbicides | HAX1, MTX1, CYP4X1 | LMNA 2455/4885POLB 4018/4885SOS1 1890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.