Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | F2R | P25116 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 5/20 | 0.46 |
| ▸ | NTSR2 | O95665 | 5/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PEPD | P12955 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417589 | 1.00 | OPRK1 (0.50) | OPRK1F2RACENTSR2NTSR1 | |
| SCHEMBL416859 | 0.92 | NTSR2 (0.49) | F2RNTSR2NTSR1F2 | |
| SCHEMBL416858 | 0.92 | NTSR2 (0.49) | F2RNTSR2NTSR1F2 | |
| SCHEMBL416536 | 0.91 | OPRK1 (0.46) | OPRK1F2RACENTSR2NTSR1 | |
| SCHEMBL416535 | 0.91 | OPRK1 (0.46) | OPRK1F2RACENTSR2NTSR1 | |
| SCHEMBL416569 | 0.90 | OPRK1 (0.45) | OPRK1F2RACENTSR2NTSR1 | |
| SCHEMBL416570 | 0.90 | OPRK1 (0.45) | OPRK1F2RACENTSR2NTSR1 | |
| SCHEMBL417341 | 0.88 | OPRK1 (0.44) | OPRK1F2RACENTSR2NTSR1 | |
| SCHEMBL417342 | 0.88 | OPRK1 (0.44) | OPRK1F2RACENTSR2NTSR1 | |
| SCHEMBL29524168 | 0.87 | OPRK1 (0.53) | OPRK1ACENTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120020878-A1 | FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2012-01-26 | — | — | US | claimed |
| US-20120020878-A1 | FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2012-01-26 | — | — | US | disclosed |