SCHEMBL417342

CSCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	OPRK1	P41145	1/20	0.44

▸	ACE	P12821	2/20	0.42

▸	F2R	P25116	2/20	0.41

▸	NTSR2	O95665	2/20	0.40

▸	NTSR1	P30989	2/20	0.40

▸	CALCR	P30988	3/20	0.40

▸	CXCR4	P61073	1/20	0.40

▸	APLNR	P35414	2/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL417341	1.00	OPRK1 (0.44)	OPRK1ACEF2RNTSR2NTSR1
SCHEMBL416570	0.95	OPRK1 (0.45)	OPRK1ACEF2RNTSR2NTSR1
SCHEMBL416569	0.95	OPRK1 (0.45)	OPRK1ACEF2RNTSR2NTSR1
SCHEMBL416535	0.94	OPRK1 (0.46)	OPRK1ACEF2RNTSR2NTSR1
SCHEMBL416536	0.94	OPRK1 (0.46)	OPRK1ACEF2RNTSR2NTSR1
SCHEMBL417518	0.93	OPRM1 (0.45)	NTSR2NTSR1CALCRCXCR4APLNR
SCHEMBL417517	0.93	OPRM1 (0.45)	NTSR2NTSR1CALCRCXCR4APLNR
SCHEMBL416629	0.90	OPRK1 (0.55)	OPRK1ACECALCR
SCHEMBL416628	0.90	OPRK1 (0.55)	OPRK1ACECALCR
SCHEMBL414730	0.88	NTSR2 (0.48)	NTSR2NTSR1APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20120020878-A1	FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS	CHILDREN'S HOSPITAL MEDICAL CENTER (US)	2012-01-26	—	—	US	disclosed