⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16393987 | 0.94 | ALDH1A1 (0.56) | — | |
| SCHEMBL42579 | 0.87 | ALDH1A1 (0.47) | — | |
| SCHEMBL352236 | 0.87 | ALDH1A1 (0.47) | — | |
| SCHEMBL448510 | 0.84 | ALDH1A1 (0.44) | — | |
| SCHEMBL447031 | 0.84 | ALDH1A1 (0.44) | — | |
| SCHEMBL139458 | 0.84 | ALDH1A1 (0.44) | — | |
| Biphenyl SCHEMBL29268822 | 0.82 | ALDH1A1 (0.50) | — | |
| SCHEMBL27907573 | 0.82 | ALDH1A1 (0.50) | — | |
| SCHEMBL10514463 | 0.82 | ALDH1A1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL27482920 | 0.82 | CHRNB4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2647 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024120467-A1 | PHOSPHORAMIDATE MONOSACCHARIDES, PHARMACEUTICAL COMPOSITIONS, AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | SURIO THERAPEUTICS CO. LTD (CN) | 2024-06-13 | — | — | WO | claimed |
| US-20240140915-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-05-02 | — | — | US | claimed |
| US-20240067612-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-02-29 | — | — | US | claimed |
| WO-2024033454-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | claimed |
| WO-2024010782-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | claimed |
| US-20230416205-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | TENVIE THERAPEUTICS, INC. | 2023-12-28 | — | — | US | claimed |
| US-20230357255-A1 | IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES AS A2A / A2B INHIBITORS | INCYTE CORPORATION | 2023-11-09 | — | — | US | claimed |
| EP-4247376-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | Denali Therapeutics Inc. (US) | 2023-09-27 | — | — | EP | claimed |
| CN-116507608-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2023-07-28 | — | — | CN | claimed |
| US-11673894-B2 | Imidazopyrimidines and triazolopyrimidines as A2A / A2B inhibitors | INCYTE CORPORATION (US) | 2023-06-13 | — | — | US | claimed |
| EP-0390693-B1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1993-08-25 | — | — | EP | claimed |
| EP-0541407-A1 | Nitrogen containing bicyclic derivatives, method for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-05-12 | — | — | EP | claimed |
| EP-0390693-A1 | Thioformamide derivatives | RHONE-POULENC SANTE (FR) | 1990-10-03 | — | — | EP | claimed |
| EP-0296452-A1 | Azolylmethylcyclopropyl-carbinol derivatives | BAYER AG (DE) | 1988-12-28 | — | — | EP | claimed |
| US-4739074-A | Adamantane spiro-pyrrolidine derivatives | PENNWALT CORPORATION (US) | 1988-04-19 | — | — | US | claimed |
| EP-0237028-A1 | N-(phenyl) or n-(phenylcyclopropyl)-2,5-dihydro-2-oxo-4, (substituted phenyl) amino-3-furancarboxamide derivatives | PENNWALT CORPORATION (US) | 1987-09-16 | — | — | EP | claimed |
| US-4625040-A | N-(phenyl) or N-(phenylcyclopropyl)-2,5-dihydro-2-oxo-4[(substituted phenyl)amino]-3-furancarboxamide derivatives | PENNWALT CORPORATION (US) | 1986-11-25 | — | — | US | claimed |
| EP-0076557-B1 | PEPTIDES AND PSEUDOPEPTIDES IN WHICH THE N TERMINUS BEARS TWO SUBSTITUENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-11-13 | — | — | EP | claimed |
| US-4421744-A | OPIATE RECEPTOR ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-12-20 | — | — | US | claimed |
| EP-0076557-A2 | Peptides and pseudopeptides in which the N terminus bears two substituents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-04-13 | — | — | EP | claimed |