SCHEMBL42579

SCHEMBL42579

c1ccc([C]2CCCC2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
CHRNB4 P30926 1/20 0.46
CHRNA3 P32297 1/20 0.46
TSHR P16473 1/20 0.45
HPGD P15428 2/20 0.39
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
MAPK1 P28482 1/20 0.36
APOBEC3A P31941 1/20 0.36
HTT P42858 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
CFTR P13569 1/20 0.36
GOPC Q9HD26 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
CYP1A2 P05177 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C19 P33261 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL447031 0.97 ALDH1A1 (0.44) ALDH1A1CHRNB4CHRNA3TSHRHPGD
SCHEMBL139458 0.97 ALDH1A1 (0.44) ALDH1A1CHRNB4CHRNA3TSHRHPGD
SCHEMBL448510 0.97 ALDH1A1 (0.44) ALDH1A1CHRNB4CHRNA3TSHRHPGD
Biphenyl SCHEMBL29268822 0.94 ALDH1A1 (0.50) ALDH1A1CHRNB4CHRNA3TSHRHPGD
Hydrochloric Acid SCHEMBL27482920 0.94 CHRNB4 (0.43) ALDH1A1CHRNB4CHRNA3TSHRHPGD
SCHEMBL352236 0.94 ALDH1A1 (0.47) ALDH1A1CHRNB4CHRNA3TSHRNPC1
SCHEMBL27716629 0.92 ALDH1A1 (0.47) ALDH1A1CHRNB4CHRNA3TSHRHPGD
SCHEMBL8938023 0.92 ALDH1A1 (0.47) ALDH1A1CHRNB4CHRNA3TSHRHPGD
SCHEMBL27907573 0.88 ALDH1A1 (0.50) ALDH1A1CHRNB4CHRNA3MAPK1TAAR1
SCHEMBL41762 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903651-A Selenium-containing luminescent compound and application thereof in electronic device 浙江华显光电科技有限公司 2023-10-20 CN claimed
EP-4165033-A1 SHP2 INHIBITORS, COMPOSITIONS AND USES THEREOF Betta Pharmaceuticals Co., Ltd (CN) 2023-04-19 EP claimed
WO-2021249449-A1 SHP2 INHIBITORS, COMPOSITIONS AND USES THEREOF BETTA PHARMACEUTICALS CO., LTD (CN) 2021-12-16 WO claimed
CN-109851615-B Process for purifying penehyclidine 上海旭东海普药业有限公司 2021-06-08 CN claimed
CN-109503405-B Synthesis method of N-N-propyl amide 中国农业大学 2021-04-16 CN claimed
CN-105753682-B A kind of preparation method of phenylcyclopentyl ketone 中国科学院成都有机化学有限公司 2018-01-09 CN claimed
CN-105753682-A Preparation method of cyclopentyl phenyl ketone 中国科学院成都有机化学有限公司 2016-07-13 CN claimed
CN-105542169-A Preparation method for alkoxy functionalized polysiloxane INST OF APPLIED CHEMISTRY JIANGXI ACAD OF SCIENCES 2016-05-04 CN claimed
EP-2231683-B1 SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE THEREOF IN HYDROFORMYLATION PROCESSES DOW GLOBAL TECHNOLOGIES LLC (US) 2016-03-23 EP claimed
CN-103328446-B Be used for the treatment of the new 4-Amino-N-hydroxy-benzamide of cancer HOFFMAN-LA ROCHE LTD. (CH) 2016-01-20 CN claimed
US-6288120-B1 Prevention of loss and restoration of bone mass by certain prostaglandin agonists PFIZER INC. 2001-09-11 US claimed
EP-1053224-A1 BIPHENYLSULFONYL CYANAMIDES, METHOD FOR THE PRODUCTION THEREOF AND THEIR UTILIZATION AS A MEDICAMENT Aventis Pharma Deutschland GmbH (DE) 2000-11-22 EP claimed
WO-1999040064-A1 BIPHENYLSULFONYL CYANAMIDES, METHOD FOR THE PRODUCTION THEREOF AND THEIR UTILIZATION AS A MEDICAMENT AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 1999-08-12 WO claimed
EP-0559079-B1 Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them SYMPHAR SA (CH) 1997-08-13 EP claimed
EP-0559079-A1 Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them SYMPHAR S.A. (CH) 1993-09-08 EP claimed
US-5234942-A Treating allergic pulmonary disorders, asthma ICI AMERICAS INC. (US) 1993-08-10 US claimed
US-4997844-A Compounds for the treatment of allergic or inflammatory diseases or shock conditions ICI AMERICAS INC. (US) 1991-03-05 US claimed
EP-0179619-B1 HETEROCYCLIC AMIDES ICI AMERICAS INC. (US) 1990-09-05 EP claimed
US-4626597-A ANTIULCER, ANTIFERTILITY AGENTS FARMITALIA CARLO ERBA, S.P.A. (IT) 1986-12-02 US claimed
EP-0179619-A1 Heterocyclic amides ICI AMERICAS INC. (US) 1986-04-30 EP claimed