SCHEMBL41776

SCHEMBL41776

Cc1cc(O)ccc1CO

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 7/20 0.47
ESR1 P03372 6/20 0.47
TYR P14679 2/20 0.44
HSD17B1 P14061 1/20 0.44
CYP3A4 P08684 2/20 0.42
CHRM1 P11229 1/20 0.42
ALOX15 P16050 1/20 0.42
MAOA P21397 1/20 0.42
TBXA2R P21731 1/20 0.42
ADRA1A P35348 1/20 0.42
HTR2B P41595 1/20 0.42
SHBG P04278 1/20 0.42
TSHR P16473 1/20 0.41
RECQL P46063 1/20 0.41
ACHE P22303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69172 0.83 ESR2 (0.49) ESR2ESR1TYRHSD17B1CYP3A4
SCHEMBL8752791 0.83 TYR (0.58) ESR2ESR1TYRCYP3A4CHRM1
SCHEMBL1665310 0.81 SHBG (0.47) ESR2ESR1TYRHSD17B1CYP3A4
SCHEMBL31305640 0.81 ESR2 (0.47) ESR2ESR1TYRHSD17B1CYP3A4
SCHEMBL2018825 0.81 ESR2 (0.47) ESR2ESR1TYRHSD17B1CYP3A4
SCHEMBL4394169 0.79 ESR2 (0.46) ESR2ESR1TYRHSD17B1CYP3A4
SCHEMBL11243543 0.79 ESR2 (0.46) ESR2ESR1TYRHSD17B1CYP3A4
SCHEMBL10306731 0.79 ESR2 (0.46) ESR2ESR1TYRHSD17B1CYP3A4
SCHEMBL18179322 0.79 ESR2 (0.46) ESR2ESR1TYRHSD17B1CYP3A4
SCHEMBL95787 0.78 TP53 (0.48) SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1341503-B1 AGENT AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2008-02-13 EP claimed
US-5510420-A NUCLEOPHILIC GRAFTING OF PARENT POLYMER HAVING AROMATIC RINGS CONTAINING REACTIVE GROUPS HOECHST CELANESE CORPORATION (US) 1996-04-23 US claimed
EP-0686274-A1 NOVEL MATRIX RESIN FOR HIGH-TEMPERATURE STABLE PHOTOIMAGEABLE COMPOSITIONS HOECHST CELANESE CORPORATION (US) 1995-12-13 EP claimed
WO-1994019724-A1 NOVEL MATRIX RESIN FOR HIGH-TEMPERATURE STABLE PHOTOIMAGEABLE COMPOSITIONS HOECHST CELANESE CORPORATION (US) 1994-09-01 WO claimed
WO-2026087651-A1 CYCLOPROPANE-ARYL COMPOUNDS FOR THE TREATMENT OF CANCER SANOFI (FR) 2026-04-30 WO disclosed
CN-119032076-A Novel compounds and uses thereof 株式会社安提昂 2024-11-26 CN disclosed
US-12049444-B2 Monomethyl fumarate precursor drug compounds and pharmaceutical compositions thereof AGATHONBIO CO., LTD. (KR) 2024-07-30 US disclosed
US-20230416460-A1 COMPOUND, RESIN COMPOSITION, RESIN SHEET, RESIN CURED PRODUCT, AND LAMINATED SUBSTRATE TDK CORPORATION (JP) 2023-12-28 US disclosed
WO-2023239171-A1 NOVEL COMPOUND AND USE THEREOF 주식회사 엑티브온 2023-12-14 WO disclosed
CN-116490355-A Compound, resin composition, resin sheet, resin cured product, and laminated substrate TDK株式会社 2023-07-25 CN disclosed
WO-2022209495-A1 COMPOUND, RESIN COMPOSITION, RESIN SHEET, RESIN CURED OBJECT, AND LAMINATED SUBSTRATE TDK株式会社 2022-10-06 WO disclosed
US-20210387939-A1 MONOMETHYL FUMARATE PRECURSOR DRUG COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF AGATHONBIO CO., LTD. (KR) 2021-12-16 US disclosed
EP-0386639-B1 Process for preparing para-hydroxybenzyl alcohol MITSUBISHI PETROCHEMICAL CO (JP) 1994-09-28 EP disclosed
WO-1994019724-A1 NOVEL MATRIX RESIN FOR HIGH-TEMPERATURE STABLE PHOTOIMAGEABLE COMPOSITIONS HOECHST CELANESE CORPORATION (US) 1994-09-01 WO disclosed
EP-0485613-A1 PROCESS FOR PARA-METHYLOLATING PHENOLIC COMPOUND MITSUBISHI CHEMICAL CORPORATION (JP) 1992-05-20 EP disclosed
US-5059610-A QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1991-10-22 US disclosed
US-5019656-A Hydroxymethylation of a Phenol, Basic Catalyst, Crown Compound MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-05-28 US disclosed
EP-0386639-A1 Process for preparing para-hydroxybenzyl alcohol MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1990-09-12 EP disclosed
US-4920132-A Quinoline derivatives and use thereof as antagonists of leukotriene D4 RORER PHARMACEUTICAL CORP. (US) 1990-04-24 US disclosed
WO-1989004305-A1 QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 RORER INTERNATIONAL (OVERSEAS) INC. (US) 1989-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210387939-A1 MONOMETHYL FUMARATE PRECURSOR DRUG COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FH, FPGS, FAH ESR2 3315/4885ESR1 3368/4885TYR 4110/4885
US-12049444-B2 Monomethyl fumarate precursor drug compounds and pharmaceutical compositions thereof FH, FPGS, FAH ESR2 3315/4885ESR1 3368/4885TYR 4110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.