Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 17/20 | 0.54 |
| ▸ | CES1 | P23141 | 4/20 | 0.54 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4180026 | 0.78 | FAAH (0.68) | FAAHCES1 | |
| SCHEMBL4189345 | 0.75 | FAAH (0.66) | FAAHCES1 | |
| Hydrochloric Acid SCHEMBL4189029 | 0.74 | FAAH (0.59) | FAAHCES1DAGLA | |
| SCHEMBL13875524 | 0.72 | FAAH (0.72) | FAAHCES1 | |
| SCHEMBL1472048 | 0.71 | FAAH (1.00) | FAAHCES1 | |
| Hydrochloric Acid SCHEMBL4184818 | 0.70 | FAAH (0.62) | FAAHCES1 | |
| Hydrochloric Acid SCHEMBL4186982 | 0.70 | FAAH (0.97) | FAAH | |
| Trifluoroacetic Acid SCHEMBL7736001 | 0.69 | NPC1 (0.50) | FAAH | |
| SCHEMBL3196395 | 0.66 | FAAH (1.00) | FAAHCES1 | |
| Trifluoroacetic Acid SCHEMBL7723271 | 0.66 | KMT2A (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111778-A1 | 2-Keto-Oxazoles as Modulators of Fatty Acid Amide Hydrolase | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-30 | — | — | US | disclosed |
| EP-1954137-A4 | 2-KETO-OXAZOLES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2008-12-17 | — | — | EP | disclosed |
| EP-1954137-A2 | 2-KETO-OXAZOLES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007061862-A2 | 2-KETO-OXAZOLES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111778-A1 | 2-Keto-Oxazoles as Modulators of Fatty Acid Amide Hydrolase | FAAH, FAAH2, HCRTR2 | FAAH 1/4885CES1 87/4885DAGLA 664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.