Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.41 |
| ▸ | ME2 | P23368 | 1/20 | 0.41 |
| ▸ | ME1 | P48163 | 1/20 | 0.41 |
| ▸ | ME3 | Q16798 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344943 | 0.86 | IP6K1 (0.43) | LMNAHTT | |
| SCHEMBL4181229 | 0.85 | CASP6 (0.54) | ALKEGFRENPP2MAPT | |
| SCHEMBL2723108 | 0.84 | ALK (0.53) | AKR1C3ALKALDH1A1LMNAMAPT | |
| SCHEMBL2724815 | 0.81 | MAPT (0.54) | ALKEGFRALDH1A1LMNAMAPT | |
| SCHEMBL29673386 | 0.79 | MAPT (0.46) | POLBALDH1A1KDM4ELMNAGAA | |
| SCHEMBL29771877 | 0.78 | GAA (0.56) | ALDH1A1KDM4EGAAMAPTHTT | |
| SCHEMBL409735 | 0.78 | GAA (0.56) | ALDH1A1KDM4EGAAMAPTHTT | |
| Hydrochloric Acid SCHEMBL3502999 | 0.77 | MAPT (0.55) | ALDH1A1KDM4EGAAMAPTHTT | |
| SCHEMBL27925817 | 0.76 | CREBBP (0.36) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL13362063 | 0.75 | MAPT (0.58) | POLBALDH1A1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061299-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |