Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 3/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344943 | 0.88 | IP6K1 (0.43) | CASP6GFERCREBBPRORC | |
| SCHEMBL2724815 | 0.85 | MAPT (0.54) | PDK2ALKMEN1MAPTKMT2A | |
| SCHEMBL4178461 | 0.85 | AKR1C3 (0.46) | ALKMAPTENPP2EGFR | |
| SCHEMBL2205957 | 0.84 | CASP6 (0.59) | CASP6GFERALKMEN1MAPT | |
| SCHEMBL29771877 | 0.82 | GAA (0.56) | GFERPDK2MEN1MAPTKMT2A | |
| SCHEMBL409735 | 0.82 | GAA (0.56) | GFERPDK2MEN1MAPTKMT2A | |
| SCHEMBL16752966 | 0.82 | CASP6 (0.54) | CASP6GFERALKMEN1MAPT | |
| SCHEMBL28469637 | 0.82 | CASP6 (0.56) | CASP6GFERPDK2ALKMEN1 | |
| Hydrochloric Acid SCHEMBL3502999 | 0.81 | MAPT (0.55) | GFERPDK2MEN1MAPTKMT2A | |
| SCHEMBL29673386 | 0.81 | MAPT (0.46) | PDK2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061299-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |