Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 4/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4182143 | 0.91 | S1PR1 (0.48) | S1PR1S1PR3SIRT2HSD11B1TRPV3 | |
| SCHEMBL9440941 | 0.81 | SIRT2 (0.56) | S1PR1S1PR3SIRT2TLR8 | |
| SCHEMBL9440855 | 0.80 | DAGLA (0.46) | S1PR1S1PR3SIRT2HSD11B1 | |
| SCHEMBL16217977 | 0.79 | S1PR1 (0.45) | S1PR1S1PR3SIRT2HSD11B1TLR8 | |
| SCHEMBL13731964 | 0.78 | S1PR1 (0.44) | S1PR1S1PR3HSD11B1TRPV3 | |
| Hydrochloric Acid SCHEMBL16210756 | 0.78 | S1PR1 (0.44) | S1PR1S1PR3SIRT2HSD11B1TLR8 | |
| SCHEMBL4188103 | 0.77 | S1PR1 (0.45) | S1PR1S1PR3HSD11B1HDAC1HDAC2 | |
| SCHEMBL13731856 | 0.77 | S1PR1 (0.45) | S1PR1S1PR3SIRT2HSD11B1HDAC1 | |
| SCHEMBL13733080 | 0.75 | HSD11B1 (0.42) | S1PR1S1PR3SIRT2HSD11B1TLR8 | |
| SCHEMBL13731475 | 0.74 | HSD11B1 (0.45) | S1PR1S1PR3HSD11B1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192203-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2009-07-30 | — | — | US | disclosed |
| US-20090192203-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2009-07-30 | — | — | US | disclosed |
| EP-1945620-A2 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007056366-A2 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192203-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | PPARG, PPARA, PPARD | S1PR1 1410/4885S1PR3 1308/4885SIRT2 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.