SCHEMBL4178496

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4187296	0.82	DRD2 (0.43)	DRD2CA12CA1CA9PREP
	SCHEMBL14110450	0.82	CA12 (0.48)	DRD2CA12CA1CA9FBP1
	SCHEMBL29151406	0.78	ALDH1A1 (0.45)	DRD2PKML3MBTL1KDM4EALDH1A1
	SCHEMBL4190201	0.78	DRD2 (0.50)	DRD2PKML3MBTL1MAPTSMN1; SMN2
	SCHEMBL2188571	0.78	CA12 (0.43)	CA12CA1CA9PREPKDM4E
	SCHEMBL27742489	0.77	PREP (0.41)	CA12CA1CA9FBP1PREP
	SCHEMBL4181304	0.77	CA12 (0.39)	DRD2CA12CA1CA9PREP
	SCHEMBL2292629	0.76	CA12 (0.44)	CA12CA1CA9PREP
	SCHEMBL23218551	0.75	DRD2 (0.43)	DRD2PKML3MBTL1KDM4EGAA
	SCHEMBL16318202	0.75	DRD2 (0.38)	DRD2PKML3MBTL1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.