SCHEMBL4178701

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4178622	1.00	TAAR1 (0.40)	TAAR1PTGER4PTGER3PTGER2TLR8
	SCHEMBL4178617	1.00	TAAR1 (0.40)	TAAR1PTGER4PTGER3PTGER2TLR8
	SCHEMBL4422344	0.83	TSHR (0.35)	TAAR1PTGER4PTGER3PTGER2NFE2L2
	SCHEMBL8802215	0.79	CDK4 (0.35)	PTGER4PTGER3PTGER2
	SCHEMBL4078195	0.78	TAAR1 (0.52)	TAAR1TLR8HTR2AMPOSLC6A4
	SCHEMBL15473593	0.78	TAAR1 (0.48)	TAAR1PTGER4PTGER3PTGER2HTR2A
	Hydrochloric Acid SCHEMBL5154766	0.77	TAAR1 (0.50)	TAAR1TLR8HTR2AMPOSLC6A4
	SCHEMBL15478085	0.75	TAAR1 (0.40)	TAAR1TLR8HTR2A
	SCHEMBL4172049	0.72	TAAR1 (0.38)	TAAR1NFE2L2SLC6A4
	SCHEMBL4172053	0.72	TAAR1 (0.38)	TAAR1NFE2L2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.