SCHEMBL4178704

SCHEMBL4178704

CCCC(N)(O)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5007938 1.00
SCHEMBL10874120 1.00
SCHEMBL5029032 0.85 FDPS (0.45)
SCHEMBL7920289 0.85 FDPS (0.45)
SCHEMBL27616475 0.83 FDPS (0.47)
SCHEMBL2170690 0.81 FDPS (0.48)
SCHEMBL28869364 0.79
SCHEMBL366537 0.78
SCHEMBL30153590 0.78 ARG1 (0.40)
SCHEMBL11046968 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7309719-B1 Storage stability; gabapentin and pregabalin, and neutral alpha -amino acid WARNER LAMBERT COMPANY, LLC (US) 2007-12-18 US claimed
EP-1077692-B1 AMINO ACID STABILIZED GABAPENTIN AND PREGABALIN PREPARATIONS AND PROCESS FOR PREPARING THE SAME WARNER LAMBERT CO (US) 2004-07-28 EP claimed
WO-2002031172-A2 L-THREONINE PRODUCING E. COLI STRAIN BASF AKTIENGESELLSCHAFT (DE) 2002-04-18 WO claimed
EP-1077692-A1 AMINO ACID STABILIZED GABAPENTIN AND PREGABALIN PREPARATIONS AND PROCESS FOR PREPARING THE SAME Warner-Lambert Company LLC (US) 2001-02-28 EP claimed
WO-1999059573-A9 STABILIZED PHARMACEUTICAL PREPARATIONS OF GAMMA-AMINOBUTYRIC ACID DERIVATIVES AND PROCESS FOR PREPARING THE SAME WARNER LAMBERT CO (US) 2000-05-04 WO claimed
WO-1999059573-A1 STABILIZED PHARMACEUTICAL PREPARATIONS OF GAMMA-AMINOBUTYRIC ACID DERIVATIVES AND PROCESS FOR PREPARING THE SAME WARNER-LAMBERT COMPANY (US) 1999-11-25 WO claimed
EP-0071023-A2 Method for producing L-isoleucine by fermentation AJINOMOTO CO., INC. (JP) 1983-02-09 EP claimed
US-12383522-B2 Baclofen formulations and methods of minimizing patient exposure to metabolite variations AMNEAL PHARMACEUTICALS LLC (US) 2025-08-12 US disclosed
US-11931328-B2 Stabilized formulations of 4-amino-3-substituted butanoic acid derivatives AMNEAL PHARMACEUTICALS LLC (US) 2024-03-19 US disclosed
US-20240082193-A1 BACLOFEN FORMULATIONS AND METHODS OF MINIMIZING PATIENT EXPOSURE TO METABOLITE VARIATIONS AMNEAL PHARMACEUTICALS LLC (US) 2024-03-14 US disclosed
US-11850225-B2 Baclofen formulations and methods of minimizing patient exposure to metabolite variations AMNEAL PHARMACEUTICALS LLC (US) 2023-12-26 US disclosed
US-20230218554-A1 STABILIZED FORMULATIONS OF 4-AMINO-3-SUBSTITUTED BUTANOIC ACID DERIVATIVES AMNEAL PHARMACEUTICALS LLC (US) 2023-07-13 US disclosed
US-11654124-B2 Stabilized formulations of 4-amino-3-substituted butanoic acid derivatives AMNEAL PHARMACEUTICALS LLC (US) 2023-05-23 US disclosed
WO-1995019442-A1 PRODUCTION OF L-ISOLEUCINE BY MEANS OF RECOMBINANT MICRO-ORGANISMS WITH DEREGULATED THREONINE DEHYDRATASE Forschungszentrum Jülich GmbH (DE) 1995-07-20 WO disclosed
US-5294547-A Brevibacterium and Corynebacterium cultures AJINOMOTO COMPANY, INC. (JP) 1994-03-15 US disclosed
US-5190782-A Dietetics NABISCO, INC. (US) 1993-03-02 US disclosed
EP-0519113-A1 Bacterial strains having high productivity of an amino acid and method of constructing these strains AJINOMOTO CO., INC. (JP) 1992-12-23 EP disclosed
EP-0131171-B1 CORYNEFORM BACTERIA CARRYING RECOMBINANT PLASMIDS AND THEIR USE IN THE FERMENTATIVE PRODUCTION OF L-THREONINE AND L-ISOLEUCINE AJINOMOTO CO., INC. (JP) 1987-10-21 EP disclosed
EP-0178744-A2 Shuttle vector Antibioticos, S.A. (ES) 1986-04-23 EP disclosed
EP-0071023-A2 Method for producing L-isoleucine by fermentation AJINOMOTO CO., INC. (JP) 1983-02-09 EP disclosed