SCHEMBL4178997

SCHEMBL4178997

CCCCCCCc1ccc(-c2ccc(C(=O)OC)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RARB P10826 7/20 0.69
MAPT P10636 2/20 0.69
MEN1 O00255 2/20 0.69
KMT2A Q03164 2/20 0.69
ALDH1A1 P00352 1/20 0.69
RARA P10276 1/20 0.69
MTOR P42345 1/20 0.69
CYP4A11 Q02928 2/20 0.67
CYP4F2 P78329 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.60
THRA P10827 5/20 0.56
THRB P10828 5/20 0.56
HAO1 Q9UJM8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4188800 1.00 RARB (0.69) RARBMAPTMEN1KMT2AALDH1A1
SCHEMBL2401275 1.00 RARB (0.69) RARBMAPTMEN1KMT2AALDH1A1
SCHEMBL20874436 1.00 RARB (0.69) RARBMAPTMEN1KMT2AALDH1A1
SCHEMBL19288566 0.98 RARB (0.69) RARBMAPTMEN1KMT2AALDH1A1
SCHEMBL10986414 0.95 CYP4A11 (0.73) RARBMAPTMEN1KMT2AALDH1A1
SCHEMBL14660877 0.95 CYP4A11 (0.73) RARBMAPTMEN1KMT2AALDH1A1
SCHEMBL12814607 0.95 CYP4A11 (0.73) RARBMAPTMEN1KMT2AALDH1A1
SCHEMBL6069166 0.95 CYP4A11 (0.73) RARBMAPTMEN1KMT2AALDH1A1
SCHEMBL6024028 0.95 CYP4A11 (0.73) RARBMAPTMEN1KMT2AALDH1A1
SCHEMBL4308585 0.95 CYP4A11 (0.73) RARBMAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9388338-B2 Liquid crystal mixture MERCK PATENT GMBH (DE) 2016-07-12 US disclosed
US-8377331-B2 Liquid crystals composition and liquid crystal display with patterned electrodes UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2013-02-19 US disclosed
US-8377331-B2 Liquid crystals composition and liquid crystal display with patterned electrodes UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2013-02-19 US disclosed
US-20110075074-A1 Liquid Crystals Composition and Liquid Crystal Display with Patterned Electrodes UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2011-03-31 US disclosed
US-20110075074-A1 Liquid Crystals Composition and Liquid Crystal Display with Patterned Electrodes UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2011-03-31 US disclosed
US-20090176837-A1 COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS SONY CORPORATION (JP) 2009-07-09 US disclosed
EP-1907347-A2 COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS Arcadia Pharmaceuticals Inc. (US) 2008-04-09 EP disclosed
WO-2007009083-A2 COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS ACADIA PHARMACEUTICALS INC. (US) 2007-01-18 WO disclosed
US-20060011886-A1 Liquid crystal mixture LI JI 2006-01-19 US disclosed
US-6958176-B2 Liquid crystal mixture AZ ELECTRONIC MATERIALS (GERMANY) GMBH (DE) 2005-10-25 US disclosed
EP-1319054-B1 LIQUID CRYSTAL MIXTURE CLARIANT INT LTD (CH) 2005-03-16 EP disclosed
US-20040085490-A1 Liquid crystal mixture AZ ELECTRONIC MATERIALS (GERMANY) GMBH (DE) 2004-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090176837-A1 COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS RARB, RARA, RARG RARB 1/4885MAPT 810/4885MEN1 4845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.