SCHEMBL4179

SCHEMBL4179

OB(O)c1ccc(C(F)(F)F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 1.00
TRPV6 Q9H1D0 2/20 0.73
ORAI1 Q96D31 1/20 0.73
ORAI2 Q96SN7 1/20 0.73
ORAI3 Q9BRQ5 1/20 0.73
ENPP2 Q13822 3/20 0.48
KIF11 P52732 2/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
CA2 P00918 4/20 0.46
CA1 P00915 3/20 0.46
TSHR P16473 2/20 0.46
LPL P06858 1/20 0.46
LIPG Q9Y5X9 1/20 0.46
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CA5B Q9Y2D0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6607384 0.93 MGLL (0.86) MGLLTRPV6ORAI1ORAI2ORAI3
SCHEMBL25413876 0.89 MGLL (0.79) MGLLTRPV6ORAI1ORAI2ORAI3
Alcohol SCHEMBL29154486 0.89 MGLL (0.79) MGLLTRPV6ORAI1ORAI2ORAI3
SCHEMBL14165310 0.87 MGLL (0.76) MGLLTRPV6ORAI1ORAI2ORAI3
SCHEMBL2406706 0.84 TRPV6 (1.00) MGLLTRPV6ORAI1ORAI2ORAI3
SCHEMBL28424595 0.84 MGLL (0.70) MGLLTRPV6ORAI1ORAI2ORAI3
SCHEMBL2850047 0.82 MGLL (0.68) MGLLTRPV6ORAI1ORAI2ORAI3
SCHEMBL17298962 0.82 MGLL (0.68) MGLLTRPV6ORAI1ORAI2ORAI3
SCHEMBL14477120 0.80 TRPV6 (0.67) MGLLTRPV6ORAI1ORAI2ORAI3
SCHEMBL164370 0.80 MGLL (0.67) MGLLTRPV6ORAI1ORAI2ORAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7123 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060240-A Long-acting antistatic PE packaging film material and preparation method thereof 广州星辰包装有限公司 2026-05-19 CN claimed
CN-122038010-A Lubricating grease composition with excellent heat resistance stability, and preparation method and application thereof 思潞博(河南)新材料有限公司 2026-05-15 CN claimed
US-12528777-B2 Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2026-01-20 US claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-120033221-A Silicon-based composite material, preparation method thereof and secondary battery 兰溪致德新能源材料有限公司 2025-05-23 CN claimed
CN-115020831-B Polymer solid electrolyte containing soluble additive and all-solid metal lithium battery 浙江工业大学 2025-05-13 CN claimed
CN-119912346-A Ultra-large-volume low-dielectric polyimide film, preparation method and application 安徽国风新材料技术有限公司 2025-05-02 CN claimed
CN-119391385-A Biphenyl benzyl derivative composite heat conduction oil and preparation method thereof 山东北方淄特特种油股份有限公司 2025-02-07 CN claimed
CN-115959993-B Synthesis method of 2-aryl propionic acid compound 山东中医药大学 2025-01-07 CN claimed
EP-1444981-A1 INTRACELLULAR CALCIUM CONCENTRATION INCREASE INHIBITORS Mikoshiba, Katsuhiko (JP) 2004-08-11 EP claimed
EP-1107982-B1 REVERSIBLE BORON COMPLEXES OF 1,2-(CIS)-DIOL CYCLIC PEPTIDES LILLY CO ELI (US) 2004-05-19 EP claimed
US-6590100-B2 Reacting an aromatic compound bearing a leaving group and an arylboronic acid and/or its derivatives in the presence of a base and an effective amount of a nickel catalyst RHODIA CHIMIE (FR) 2003-07-08 US claimed
EP-1313560-A1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION YALE UNIVERSITY (US) 2003-05-28 EP claimed
US-6562989-B2 Bicyclopentyl iron ligand and transition metal catalyst YALE UNIVERSITY 2003-05-13 US claimed
US-20030008768-A1 Catalyst for aromatic C-O, C-N, and C-C bond formation NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-01-09 US claimed
US-20020173652-A1 Process for preparing a polyaromatic compound SHASUN PHARMA SOLUTIONS, INC. 2002-11-21 US claimed
US-20020165411-A1 Sterically hindered phosphine ligands and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-11-07 US claimed
WO-2002048160-A1 STERICALLY HINDERED PHOSPHINE LIGANDS AND USES THEREOF YALE UNIVERSITY (US) 2002-06-20 WO claimed
WO-2002011883-A1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION YALE UNIVERSITY (US) 2002-02-14 WO claimed