Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | DDO | Q99489 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.34 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4445914 | 0.79 | CYP1A2 (0.44) | LMNAERCC1DNASE1FEN1ERCC4 | |
| SCHEMBL10617 | 0.75 | DAO (0.60) | DAOBRD4DDOKDRCHEK1 | |
| SCHEMBL29370120 | 0.75 | DAO (0.60) | DAOBRD4DDOKDRCHEK1 | |
| Hydrochloric Acid SCHEMBL6506378 | 0.73 | DAO (0.58) | DAOBRD4DDOKDRCHEK1 | |
| SCHEMBL27818462 | 0.73 | DAO (0.58) | DAOBRD4DDOKDRCHEK1 | |
| Formaldehyde SCHEMBL28001667 | 0.72 | DAO (0.56) | DAOBRD4DDOKDRCHEK1 | |
| Pyrrole SCHEMBL28035663 | 0.71 | BRD4 (0.51) | DAOBRD4DDOKDRCHEK1 | |
| Acetic Acid SCHEMBL28431508 | 0.70 | DAO (0.54) | DAOBRD4DDOKDRCHEK1 | |
| SCHEMBL27684263 | 0.69 | BRD4 (0.53) | DAOBRD4DDOKDRCHEK1 | |
| SCHEMBL28589648 | 0.68 | KDR (0.53) | DAOBRD4DDOKDRCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2413974-B1 | CONJUGATED ANTIMICROBIAL AGENTS | TECHNION RES & DEV FOUNDATION (IL) | 2016-03-23 | — | — | EP | disclosed |
| US-9149536-B2 | Conjugated antimicrobial agents | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2015-10-06 | — | — | US | disclosed |
| US-20140357591-A1 | CONJUGATED ANTIMICROBIAL AGENTS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-12-04 | — | — | US | disclosed |
| US-8809286-B2 | Conjugated antimicrobial agents | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-08-19 | — | — | US | disclosed |
| EP-2413974-A1 | CONJUGATED ANTIMICROBIAL AGENTS | Technion Research & Development Foundation Ltd. (IL) | 2012-02-08 | — | — | EP | disclosed |
| US-20120018334-A1 | CONJUGATED ANTIMICROBIAL AGENTS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2012-01-26 | — | — | US | disclosed |
| WO-2010113151-A1 | CONJUGATED ANTIMICROBIAL AGENTS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357591-A1 | CONJUGATED ANTIMICROBIAL AGENTS | OGT, IMMT, DNTT | DAO 1028/4885BRD4 3403/4885DDO 1072/4885 |
| US-20120018334-A1 | CONJUGATED ANTIMICROBIAL AGENTS | OGT, IMMT, DNTT | DAO 1028/4885BRD4 3403/4885DDO 1072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.