Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | RECQL | P46063 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4179664 | 1.00 | L3MBTL1 (0.49) | L3MBTL1KMT2ATDP1HTTRECQL | |
| SCHEMBL1320208 | 0.87 | PKM (0.51) | L3MBTL1KMT2ATDP1HTTRECQL | |
| SCHEMBL4172219 | 0.87 | PKM (0.51) | L3MBTL1KMT2ATDP1HTTRECQL | |
| SCHEMBL4191076 | 0.85 | KMT2A (0.45) | L3MBTL1KMT2ATDP1HTTRECQL | |
| SCHEMBL4191074 | 0.85 | KMT2A (0.45) | L3MBTL1KMT2ATDP1HTTRECQL | |
| SCHEMBL4169402 | 0.83 | TDP1 (0.43) | L3MBTL1KMT2ATDP1HTTRECQL | |
| SCHEMBL4169406 | 0.83 | TDP1 (0.43) | L3MBTL1KMT2ATDP1HTTRECQL | |
| SCHEMBL12123694 | 0.83 | HTT (0.43) | L3MBTL1KMT2ATDP1HTTRECQL | |
| SCHEMBL5181905 | 0.82 | L3MBTL1 (0.53) | L3MBTL1KMT2ATDP1HTTRECQL | |
| SCHEMBL5181910 | 0.82 | L3MBTL1 (0.53) | L3MBTL1KMT2ATDP1HTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018183-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2009-01-15 | — | — | US | claimed |
| US-7442807-B2 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2008-10-28 | — | — | US | claimed |
| EP-1414440-B1 | N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR LIGANDS | ACTION PHARMA AS (DK) | 2007-01-10 | — | — | EP | claimed |
| US-20060148798-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2006-07-06 | — | — | US | claimed |
| EP-1414440-A1 | N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR LIGANDS | Melacure Therapeutics AB (SE) | 2004-05-06 | — | — | EP | claimed |
| WO-2003013509-A1 | N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTION LIGANDS | MELACURE THERAPEUTICS AB (SE) | 2003-02-20 | — | — | WO | claimed |
| US-20090018183-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2009-01-15 | — | — | US | disclosed |
| US-7442807-B2 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2008-10-28 | — | — | US | disclosed |
| US-7186748-B2 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2007-03-06 | — | — | US | disclosed |
| EP-1414440-B1 | N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR LIGANDS | ACTION PHARMA AS (DK) | 2007-01-10 | — | — | EP | disclosed |
| US-20060148798-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2006-07-06 | — | — | US | disclosed |
| EP-1414440-A1 | N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR LIGANDS | Melacure Therapeutics AB (SE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003013509-A1 | N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTION LIGANDS | MELACURE THERAPEUTICS AB (SE) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018183-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | MC1R, MC5R, MC3R | L3MBTL1 1174/4885KMT2A 2311/4885TDP1 3298/4885 |
| US-20060148798-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | MC1R, MC5R, MC3R | L3MBTL1 1174/4885KMT2A 2311/4885TDP1 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.