Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31087243 | 0.82 | KDM4E (0.52) | KDM4ELMNARXFP1IDO1ALDH1A1 | |
| SCHEMBL5890646 | 0.82 | KDM4E (0.52) | KDM4ELMNARXFP1IDO1ALDH1A1 | |
| SCHEMBL9018825 | 0.76 | PTPN1 (0.42) | KDM4ELMNARXFP1IDO1ALDH1A1 | |
| SCHEMBL7411224 | 0.73 | ALDH1A1 (0.58) | KDM4ELMNARXFP1IDO1ALDH1A1 | |
| SCHEMBL30478007 | 0.73 | ALDH1A1 (0.58) | KDM4ELMNARXFP1IDO1ALDH1A1 | |
| SCHEMBL16856525 | 0.73 | KDM4E (0.39) | KDM4ELMNARXFP1IDO1ALDH1A1 | |
| SCHEMBL812717 | 0.73 | ALDH1A1 (0.43) | KDM4ELMNARXFP1IDO1ALDH1A1 | |
| SCHEMBL18214562 | 0.71 | KDM4E (0.44) | KDM4ELMNARXFP1IDO1ALDH1A1 | |
| SCHEMBL14252184 | 0.71 | CYP1A2 (0.38) | KDM4ELMNARXFP1IDO1ALDH1A1 | |
| SCHEMBL24510859 | 0.70 | RAB9A (0.46) | KDM4ELMNARXFP1IDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807481-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2018-06-20 | — | — | EP | disclosed |
| EP-1807481-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2018-06-20 | — | — | EP | disclosed |
| US-8940407-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2015-01-27 | — | — | US | disclosed |
| US-8940407-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2015-01-27 | — | — | US | disclosed |
| US-8940407-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2015-01-27 | — | — | US | disclosed |
| US-20090072712-A1 | Organic Electroluminescent Device | MERCK PATENT GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
| US-20090072712-A1 | Organic Electroluminescent Device | MERCK PATENT GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
| US-20090072712-A1 | Organic Electroluminescent Device | MERCK PATENT GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
| EP-1807481-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Merck Patent GmbH (DE) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006048268-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2006-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090072712-A1 | Organic Electroluminescent Device | MAL2, ELAVL1, ELAVL3 | KDM4E 2370/4885LMNA 3781/4885RXFP1 4844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.