Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL417615 | 0.97 | PTPN22 (0.37) | PIM1CDK2MEN1KMT2AGAA | |
| SCHEMBL10054265 | 0.86 | CDK2 (0.31) | CDK2 | |
| SCHEMBL5374043 | 0.81 | CDK2 (0.42) | CDK2MEN1KMT2AGAAG6PD | |
| SCHEMBL9350116 | 0.79 | PTPN22 (0.54) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL29689091 | 0.77 | ALOX15 (0.42) | PIM1MEN1KMT2AG6PDCASP7 | |
| SCHEMBL7855237 | 0.77 | ALOX15 (0.42) | PIM1MEN1KMT2AG6PDCASP7 | |
| Hydrochloric Acid SCHEMBL28756357 | 0.74 | ALOX15 (0.40) | PIM1MEN1KMT2AGAAG6PD | |
| Hydrochloric Acid SCHEMBL28281094 | 0.74 | ALOX15 (0.40) | PIM1MEN1KMT2AGAAG6PD | |
| SCHEMBL9833459 | 0.72 | PLAU (0.40) | GAAALDH1A1MAPK1LMNAALOX15 | |
| SCHEMBL3885875 | 0.72 | GAA (0.37) | PIM1MEN1KMT2AGAAG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021897-A1 | RING COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-26 | — | — | US | disclosed |
| US-20120021897-A1 | RING COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-26 | — | — | US | disclosed |
| US-20120021897-A1 | RING COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-26 | — | — | US | disclosed |
| EP-2399918-A1 | RING COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2011-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021897-A1 | RING COMPOUND | NR4A2, NR4A1, NR0B1 | PIM1 4536/4885CDK2 557/4885MEN1 1961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.